{"id":"W2091401847","doi":"10.1038/nature08994","title":"Myosin II contributes to cell-scale actin network treadmilling through network disassembly","year":2010,"lang":"en","type":"article","venue":"Nature","topic":"Cellular Mechanics and Interactions","field":"Biochemistry, Genetics and Molecular Biology","cited_by":396,"is_retracted":false,"has_abstract":false,"ca_institutions":"McGill University","funders":"National Institute of Allergy and Infectious Diseases; National Institute of General Medical Sciences; Howard Hughes Medical Institute","keywords":"Treadmilling; Myosin; Cell biology; Motility; Actin; Actin remodeling; Microfilament; Chemistry; Biology; Biophysics; Cytoskeleton; Actin cytoskeleton; Cell; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001594081,0.0001930171,0.000171552,0.00001707481,0.0003408316,0.00005356133,0.0002454153,0.001211775,0.00006525066],"category_scores_gemma":[0.00006964834,0.0001786494,0.0001429728,0.0002005547,0.00001799615,0.000006512186,0.0001822106,0.001316457,0.00002294757],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001231355,"about_ca_system_score_gemma":0.00004432398,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001794909,"about_ca_topic_score_gemma":0.0004459626,"domain_scores_codex":[0.998863,0.00002880964,0.0001797612,0.0003920791,0.0001108822,0.0004254397],"domain_scores_gemma":[0.9992502,0.00002550529,0.00007320387,0.0004313256,0.0001125138,0.0001072425],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00006202461,0.00005940204,0.0001889761,0.00000373843,0.0000318095,0.000001650409,0.00003292043,0.0003468076,0.8367221,0.001250312,0.1608203,0.0004799897],"study_design_scores_gemma":[0.0001980547,0.0001063449,0.0001220089,0.00001317065,0.00002062511,0.000005325617,0.0000254587,0.00008250738,0.3723906,0.0004669121,0.6264116,0.0001574325],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9706007,0.003276028,0.009326759,0.002659019,0.004886203,0.0003769896,0.00004073692,0.00004480108,0.008788826],"genre_scores_gemma":[0.9864911,0.0001256971,0.003792855,0.003322234,0.0025986,0.00002478941,0.0002341861,0.00003722206,0.003373265],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.4655913,"threshold_uncertainty_score":0.9346321,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.00382658363408726,"score_gpt":0.2471418717709497,"score_spread":0.2433152881368625,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}