{"id":"W2091428457","doi":"10.1182/blood-2004-10-4144","title":"Telomere loss, senescence, and genetic instability in CD4+ T lymphocytes overexpressing hTERT","year":2005,"lang":"en","type":"article","venue":"Blood","topic":"Telomeres, Telomerase, and Senescence","field":"Medicine","cited_by":58,"is_retracted":false,"has_abstract":true,"ca_institutions":"BC Cancer Agency; University of British Columbia Hospital","funders":"National Institute of Allergy and Infectious Diseases","keywords":"Telomerase reverse transcriptase; Telomere; Telomerase; Biology; Senescence; Molecular biology; Population; Transfection; Green fluorescent protein; Cancer research; Cell culture; Cell biology; Gene; Genetics; Medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002364167,0.0001633338,0.0001326376,0.0002820636,0.0001188047,0.0002676527,0.0001091076,0.0002919058,0.0004900958],"category_scores_gemma":[0.0003530656,0.0001206031,0.00009982345,0.000160551,0.000196432,0.0002222616,0.0001434425,0.0003570472,0.0001332321],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002227419,"about_ca_system_score_gemma":0.0001274393,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002168635,"about_ca_topic_score_gemma":0.0003517844,"domain_scores_codex":[0.9998957,0.00002912871,0.00001118013,0.00001747435,0.00002467576,0.00002186702],"domain_scores_gemma":[0.9997811,0.00005884363,0.00008213666,0.00002057221,0.00001585712,0.00004156204],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0005947857,0.0000747271,0.01437042,0.00003832421,0.00001591152,0.0007468353,0.00009342803,0.000142543,0.9775696,0.0001333325,0.00005110624,0.006168891],"study_design_scores_gemma":[0.0001548457,0.003838111,0.2122555,0.0000291399,0.000111957,0.01367306,0.0002260196,0.001931315,0.7644,0.0006852752,0.00267488,0.00001988291],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9984188,0.001066784,0.0002793759,0.00002287565,0.000002323887,0.000002627867,0.0000264185,0.000007289301,0.0001733735],"genre_scores_gemma":[0.9984653,0.0006071319,0.000262398,0.00002200351,0.000008859482,0.000007646606,0.0001006368,0.000003407699,0.0005225996],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0004900958,"threshold_uncertainty_score":0.001639545,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01026105673149884,"score_gpt":0.2395696486117373,"score_spread":0.2293085918802384,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}