{"id":"W2091474534","doi":"10.1016/j.biomaterials.2008.09.057","title":"In vitro chelating, cytotoxicity, and blood compatibility of degradable poly(ethylene glycol)-based macromolecular iron chelators","year":2008,"lang":"en","type":"article","venue":"Biomaterials","topic":"Hemoglobinopathies and Related Disorders","field":"Medicine","cited_by":97,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of British Columbia","funders":"","keywords":"Chelation; Polyethylene glycol; Chemistry; Copolymer; PEG ratio; Polymer chemistry; Ethylene glycol; Gel permeation chromatography; Cytotoxicity; Nuclear chemistry; In vitro; Polymer; Biochemistry; Organic chemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003467876,0.0002148204,0.0006191437,0.000151562,0.00007475293,0.000009502192,0.00007390406,0.0002598041,0.0001332279],"category_scores_gemma":[0.0001030961,0.0001811108,0.00008412329,0.0002486682,0.0002682143,0.00005473447,0.00005195264,0.00004011701,0.000007099862],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0000400311,"about_ca_system_score_gemma":0.0001180806,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001057259,"about_ca_topic_score_gemma":0.000007925298,"domain_scores_codex":[0.9984104,0.0001156286,0.0005999179,0.0003266013,0.0002337446,0.0003137073],"domain_scores_gemma":[0.9992775,0.00003964268,0.0001839271,0.0003115394,0.00004739044,0.0001399812],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0004664653,0.0004893446,0.02728066,0.0003381572,0.00003808649,0.0001581288,0.0002205673,0.000001685584,0.9709079,0.000008650209,0.00002622832,0.00006415248],"study_design_scores_gemma":[0.003694932,0.0002811709,0.04118579,0.0001208783,0.00007924359,0.0001190863,0.00004598211,0.00009543736,0.9541357,0.00003081432,0.00004314887,0.0001678482],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9974902,0.001299135,0.00001705772,0.000221405,0.0001146132,0.0005450604,0.00004092951,0.0000494785,0.0002221166],"genre_scores_gemma":[0.9979508,0.00009265832,0.00163709,0.0001731909,0.00002811598,0.00001398706,0.00003873294,0.00002631015,0.00003912753],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0167722,"threshold_uncertainty_score":0.7385484,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01234578579956427,"score_gpt":0.2429993645028824,"score_spread":0.2306535787033181,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}