{"id":"W2091492315","doi":"10.1038/ncpneuro0299","title":"Is tetrabenazine safe and effective for suppressing chorea in Huntington's disease?","year":2006,"lang":"en","type":"letter","venue":"Nature Clinical Practice Neurology","topic":"Genetic Neurodegenerative Diseases","field":"Neuroscience","cited_by":6,"is_retracted":false,"has_abstract":false,"ca_institutions":"Pacific Centre for Reproductive Medicine; University of British Columbia; Child and Family Research Institute","funders":"","keywords":"Chorea; Tetrabenazine; Huntington's disease; Neuroscience; Medicine; Disease; Psychology; Pharmacology; Psychiatry; Internal medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaresearch","metaepi_narrow","research_integrity"],"consensus_categories":["research_integrity"],"category_scores_codex":[0.0008598978,0.0007572969,0.001101739,0.0003334088,0.0002218771,0.0001773771,0.0006839836,0.002844363,0.00003422128],"category_scores_gemma":[0.0818357,0.0007191505,0.0004029041,0.0003646108,0.0007849982,0.0003507341,0.0003530471,0.01182011,0.00003890586],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002844682,"about_ca_system_score_gemma":0.0002214593,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001083196,"about_ca_topic_score_gemma":0.00001010966,"domain_scores_codex":[0.990066,0.004132173,0.001170705,0.003005504,0.0006296802,0.0009959602],"domain_scores_gemma":[0.9499904,0.04770402,0.0009448971,0.0008699838,0.0002557687,0.0002349422],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.001397566,0.0006750383,0.01048753,0.0003010302,0.00003129804,0.001592687,0.00001602454,0.00002649356,0.001759646,0.00005707633,0.98062,0.00303567],"study_design_scores_gemma":[0.002077315,0.00090618,0.05854881,0.0000439223,0.0003945273,0.00004292762,0.000001268926,0.0002768821,0.003768458,0.001424713,0.9319003,0.0006147171],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"commentary","genre_gemma":"commentary","genre_scores_codex":[0.1878825,0.0009063872,0.00004394895,0.803376,0.003351692,0.002660627,0.00058113,0.00009725749,0.001100444],"genre_scores_gemma":[0.1683708,0.0001852227,0.0004243552,0.8262036,0.003982511,0.0002676832,0.0001270847,0.0001555581,0.0002831845],"genre_candidate":"commentary","genre_consensus":"commentary","teacher_disagreement_score":0.0809758,"threshold_uncertainty_score":0.999526,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03106503639149672,"score_gpt":0.387925227451071,"score_spread":0.3568601910595743,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}