{"id":"W2091532487","doi":"10.1016/j.bpj.2011.09.032","title":"Quantification of Fluorophore Copy Number from Intrinsic Fluctuations during Fluorescence Photobleaching","year":2011,"lang":"en","type":"article","venue":"Biophysical Journal","topic":"Advanced Fluorescence Microscopy Techniques","field":"Biochemistry, Genetics and Molecular Biology","cited_by":31,"is_retracted":false,"has_abstract":false,"ca_institutions":"Dalhousie University","funders":"","keywords":"Photobleaching; Fluorophore; Biological system; Fluorescence recovery after photobleaching; Shot noise; Statistical fluctuations; Noise (video); Fluorescence; Statistical physics; Microscopy; Physics; Chemistry; Biophysics; Optics; Computer science; Biology; Artificial intelligence","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001221758,0.000802189,0.0008838283,0.0008696926,0.0005542915,0.001126285,0.001208477,0.001223401,0.001409936],"category_scores_gemma":[0.002785135,0.0005662704,0.0003948042,0.001029009,0.0007880672,0.001277195,0.0006185772,0.002142694,0.0005879049],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00122679,"about_ca_system_score_gemma":0.0007047834,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00168968,"about_ca_topic_score_gemma":0.002656376,"domain_scores_codex":[0.9989303,0.00009845129,0.00004590004,0.0003276818,0.0004797837,0.0001178971],"domain_scores_gemma":[0.9984429,0.0006788934,0.0001590882,0.000291698,0.0003282906,0.00009905915],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001347674,0.00006529791,0.001094902,0.00005329378,0.00001566555,0.00004053871,0.00009777962,0.0007786866,0.9904976,0.0003255866,0.00008855684,0.006807284],"study_design_scores_gemma":[0.000005204574,0.00004106399,0.003873006,0.000004891763,0.00001451571,0.00006593862,0.00001571397,0.01146226,0.9839212,0.0001739396,0.0004072099,0.00001510346],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.7845249,0.0009111936,0.2089406,0.0001658594,0.00009912387,0.0001933358,0.0009960032,0.001149071,0.0030199],"genre_scores_gemma":[0.8695104,0.001359456,0.1196976,0.0001437845,0.00003009676,0.0005833338,0.001952777,0.0005966225,0.006126088],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00168968,"threshold_uncertainty_score":0.008901,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01635404186700867,"score_gpt":0.2747566041034614,"score_spread":0.2584025622364527,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}