{"id":"W2091647214","doi":"10.1634/stemcells.19-5-453","title":"The SDF‐1‐CXCR4 Axis Stimulates VEGF Secretion and Activates Integrins but does not Affect Proliferation and Survival in Lymphohematopoietic Cells","year":2001,"lang":"en","type":"article","venue":"Stem Cells","topic":"Chemokine receptors and signaling","field":"Medicine","cited_by":220,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta; Canadian Blood Services","funders":"National Heart, Lung, and Blood Institute","keywords":"Biology; Cell biology; CXCR4; Integrin; Stromal cell; Protein kinase B; Chemokine receptor; Cancer research; Chemokine; Receptor; Signal transduction; Immunology; Inflammation; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00015589,0.0002142288,0.0001794056,0.0001953693,0.0001129377,0.0002690607,0.00008669924,0.0001361509,0.001997561],"category_scores_gemma":[0.0001278229,0.00008323267,0.0001742786,0.0001342815,0.0001155798,0.0001386721,0.0001257479,0.0002916232,0.0005288646],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000249714,"about_ca_system_score_gemma":0.0001785013,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006979519,"about_ca_topic_score_gemma":0.000678377,"domain_scores_codex":[0.9997928,0.00005763323,0.00002135696,0.00002328367,0.00004809856,0.00005690326],"domain_scores_gemma":[0.9999079,0.00002841375,0.00002132448,0.00001377974,0.00001122848,0.00001738123],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003625536,0.0001175319,0.001266618,0.00006718525,0.000009144973,0.0001245785,0.00003140653,0.0000808075,0.994213,0.0001622408,0.0001293905,0.003435492],"study_design_scores_gemma":[0.0001097013,0.001539697,0.02123323,0.00001324309,0.00002950305,0.0009424664,0.00008022768,0.00137132,0.9686089,0.00009064298,0.005974612,0.000006420844],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9936386,0.00307956,0.000813287,0.00006062623,0.00002475745,0.000029409,0.0004113727,0.00002762246,0.001914783],"genre_scores_gemma":[0.9955759,0.001078966,0.0007842984,0.000056578,0.00001664599,0.00004364564,0.0007452799,0.000006107481,0.001692604],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001997561,"threshold_uncertainty_score":0.006682515,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01224288539611586,"score_gpt":0.2450871053192256,"score_spread":0.2328442199231098,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}