{"id":"W2091697174","doi":"10.1016/j.carres.2011.09.015","title":"Synthesis of a Forssman antigen derivative for use in a conjugate vaccine","year":2011,"lang":"en","type":"article","venue":"Carbohydrate Research","topic":"Carbohydrate Chemistry and Synthesis","field":"Chemistry","cited_by":11,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Calgary; Alberta Glycomics Centre","funders":"","keywords":"Chemistry; Conjugate; Conjugate vaccine; Derivative (finance); Antigen; Total synthesis; Stereochemistry; Combinatorial chemistry; Chemical synthesis; Convergent synthesis; Immunogenicity; Biochemistry; Immunology; In vitro; Antibiotics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.001134735,0.0002615477,0.0005687436,0.0003428304,0.0001195709,0.00004334056,0.0005416893,0.0002673362,0.0006427356],"category_scores_gemma":[0.001936818,0.0002556576,0.0001971744,0.0007514934,0.0002257802,0.0002204745,0.0001815809,0.0003829616,0.00001150064],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001451688,"about_ca_system_score_gemma":0.0001750681,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00091296,"about_ca_topic_score_gemma":0.0002139482,"domain_scores_codex":[0.997448,0.0001230985,0.0006034825,0.0005816949,0.0004104152,0.000833266],"domain_scores_gemma":[0.9965366,0.001846277,0.0001406435,0.0007561355,0.0005267963,0.0001935532],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0006408274,0.0002392774,0.01135748,0.0004688828,0.0001096258,0.00004973308,0.00104575,0.000002916414,0.9844525,0.0004599628,0.0001092992,0.001063724],"study_design_scores_gemma":[0.0005945123,0.00004056395,0.0008415713,0.0002672533,0.0000220168,0.000002943466,0.000919787,0.0008852431,0.9945453,0.001306808,0.0003145267,0.0002594689],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.989379,0.0001120558,0.00003081825,0.00004719062,0.00002807402,0.0003104381,0.0001524728,0.00004231129,0.009897615],"genre_scores_gemma":[0.9980845,0.0001512708,0.0006375837,0.000008127101,0.00007183268,0.000512333,0.00002256107,0.00006202517,0.0004497631],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0105159,"threshold_uncertainty_score":0.9999896,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.163288393762872,"score_gpt":0.336787018832118,"score_spread":0.173498625069246,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}