{"id":"W2091790925","doi":"10.1038/nbt1102","title":"Characterization and culture of human embryonic stem cells","year":2005,"lang":"en","type":"review","venue":"Nature Biotechnology","topic":"Pluripotent Stem Cells Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":458,"is_retracted":false,"has_abstract":false,"ca_institutions":"Robarts Clinical Trials","funders":"","keywords":"Embryonic stem cell; Cell culture; Cell biology; Induced pluripotent stem cell; Stem cell; Biology; KOSR; In vitro; Karyotype; Cellular differentiation; Genetics; Chromosome; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","research_integrity"],"consensus_categories":[],"category_scores_codex":[0.0001560261,0.0003787607,0.000893485,0.0002768829,0.00006377113,0.00001454746,0.0005609057,0.006179027,0.000009761246],"category_scores_gemma":[0.00001703089,0.0003109998,0.0002118944,0.0002722668,0.0002286476,0.000002990946,0.0004429818,0.001298971,0.00001343618],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003635855,"about_ca_system_score_gemma":0.0001105365,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":9.376665e-7,"about_ca_topic_score_gemma":0.000005480072,"domain_scores_codex":[0.9983246,0.0001086197,0.0003786425,0.0006970598,0.0001672405,0.0003238342],"domain_scores_gemma":[0.9987885,0.000008415948,0.0003721337,0.0006903086,0.00008114938,0.00005951128],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.000004058953,0.00002983556,5.246558e-7,0.00239057,0.00009765098,0.000003810763,0.000004625587,2.472962e-8,0.4636816,0.0001208739,0.0005376457,0.5331288],"study_design_scores_gemma":[0.0001294758,0.0001935634,0.000001028555,0.0005971438,0.00009749865,0.0000524656,0.000004334801,5.172396e-7,0.138358,0.000002656618,0.8603343,0.0002289275],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.001389118,0.997439,0.00003660309,0.00008933323,0.0001445784,0.0005977538,0.0001727268,0.00003495387,0.00009597784],"genre_scores_gemma":[0.0006588121,0.9935015,0.0000926692,0.00002778093,0.0002246025,0.00002989718,0.0008425257,0.00005547647,0.004566662],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.8597967,"threshold_uncertainty_score":0.9999342,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01462281025421574,"score_gpt":0.3094408560201286,"score_spread":0.2948180457659128,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}