{"id":"W2091792931","doi":"10.1016/j.chom.2009.09.013","title":"Cowpox Virus Inhibits the Transporter Associated with Antigen Processing to Evade T Cell Recognition","year":2009,"lang":"en","type":"article","venue":"Cell Host & Microbe","topic":"Poxvirus research and outbreaks","field":"Immunology and Microbiology","cited_by":79,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of British Columbia","funders":"National Center for Research Resources; National Institute of Allergy and Infectious Diseases","keywords":"Biology; Cowpox virus; MHC class I; Cowpox; Antigen processing; Virology; Major histocompatibility complex; CD8; Antigen presentation; Transporter associated with antigen processing; Vaccinia; MHC restriction; Antigen; Virus; T cell; Cell biology; Immune system; Gene; Immunology; Genetics; Recombinant DNA","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002153535,0.0002133037,0.0003044234,0.0001222762,0.000195715,0.0003922404,0.0002184825,0.0004625097,0.001940976],"category_scores_gemma":[0.0002256155,0.0001598506,0.0002245876,0.0001031558,0.0001720832,0.0002893134,0.0001471691,0.000675622,0.0004606381],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004712662,"about_ca_system_score_gemma":0.0002921314,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001194955,"about_ca_topic_score_gemma":0.001122852,"domain_scores_codex":[0.9998369,0.00004053034,0.000007777321,0.00001359644,0.00003391698,0.00006720945],"domain_scores_gemma":[0.9998953,0.00003969714,0.00001415036,0.00001262229,0.00001232338,0.00002587185],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0004645314,0.00009166954,0.0004076275,0.00003617062,0.00001698804,0.0000564428,0.00001477034,0.0001536903,0.9955003,0.0004157479,0.0002019121,0.002640233],"study_design_scores_gemma":[0.00009760282,0.0005984431,0.007627236,0.000005272626,0.00001822877,0.0003163387,0.00003443158,0.003715629,0.9836113,0.0001279276,0.003840938,0.0000067208],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9960861,0.0009154447,0.0009916675,0.0001599102,0.00004071867,0.00001779474,0.000060067,0.00004256687,0.001685676],"genre_scores_gemma":[0.9956695,0.0004489492,0.0008118972,0.0000797843,0.00001644943,0.0000127279,0.0002177394,0.00001904844,0.00272389],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001940976,"threshold_uncertainty_score":0.006493151,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01425693055919929,"score_gpt":0.232554723650193,"score_spread":0.2182977930909937,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}