{"id":"W2091796767","doi":"10.1021/ol902924x","title":"Tandem Palladium-Catalyzed Addition/Cyclocarbonylation: An Efficient Synthesis of 2-Heteroquinazolin-4(<i>3H</i>)-ones","year":2010,"lang":"en","type":"article","venue":"Organic Letters","topic":"Quinazolinone synthesis and applications","field":"Chemistry","cited_by":76,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Ottawa","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Chemistry; Palladium; Catalysis; Tandem; Combinatorial chemistry; Reaction conditions; Organic chemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001927013,0.0005450906,0.0004041888,0.0002422425,0.0002260109,0.0002927858,0.0006339928,0.0003149483,0.001953328],"category_scores_gemma":[0.0001375936,0.0002217132,0.0002351876,0.0002510498,0.0001991617,0.0003271449,0.000478347,0.0004296575,0.001028531],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002777043,"about_ca_system_score_gemma":0.0003018565,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004113604,"about_ca_topic_score_gemma":0.001124342,"domain_scores_codex":[0.9998158,0.00002503048,0.00001539788,0.00005279915,0.00004210587,0.00004893967],"domain_scores_gemma":[0.999954,0.00000571714,0.0000148315,0.000005876881,0.000007811073,0.00001174456],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000162829,0.00005163208,0.0001418669,0.0002117937,0.00002732263,0.0003428472,0.00004784482,0.0006701308,0.9821513,0.0005624311,0.000290845,0.01533923],"study_design_scores_gemma":[0.00005138536,0.0002312675,0.0005152961,0.000004871993,0.00002529417,0.0003634891,0.00001212576,0.0006408709,0.9903297,0.0001208817,0.007685418,0.00001939458],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9181631,0.01095983,0.04611377,0.0003174903,0.0002596976,0.0003816764,0.001045351,0.0006669997,0.02209197],"genre_scores_gemma":[0.9706137,0.003747548,0.01797322,0.00009708949,0.00003401525,0.0001223498,0.000339409,0.00005517198,0.007017555],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001953328,"threshold_uncertainty_score":0.006534576,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.00682955659580963,"score_gpt":0.2098275108079569,"score_spread":0.2029979542121473,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}