{"id":"W2091801473","doi":"10.1016/j.ijpharm.2007.06.032","title":"Polymeric micelles for the solubilization and delivery of STAT3 inhibitor cucurbitacins in solid tumors","year":2007,"lang":"en","type":"article","venue":"International Journal of Pharmaceutics","topic":"Bioactive Compounds and Antitumor Agents","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":89,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Alberta","funders":"National Institute of Allergy and Infectious Diseases; Canadian Institutes of Health Research; Ministry of Health and Medical Education","keywords":"Solubilization; Micelle; Chemistry; Pharmacology; Dosage form; Chromatography; Medicine; Organic chemistry; Aqueous solution; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00115348,0.0001291685,0.0002078558,0.0002578598,0.00007624799,0.00002040547,0.0003264624,0.00007034963,0.00006663914],"category_scores_gemma":[0.00009046524,0.0001008263,0.0001067459,0.0001337841,0.0002073918,0.0001644854,0.00007260761,0.0003713348,0.00000109283],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00007678935,"about_ca_system_score_gemma":0.0001035275,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001383131,"about_ca_topic_score_gemma":0.00003065955,"domain_scores_codex":[0.9986476,0.00008443727,0.0006849837,0.0001098507,0.0002582102,0.0002149093],"domain_scores_gemma":[0.997953,0.0008426966,0.0005377652,0.00005073137,0.0005167336,0.00009907454],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.003815823,0.001031318,0.1485447,0.00008952908,0.0008962828,0.0001570274,0.002057777,0.001369984,0.7399427,0.0010446,0.001066625,0.0999837],"study_design_scores_gemma":[0.005764978,0.0002339049,0.0221554,0.0001160892,0.0002373613,0.0002261063,0.001374737,0.01612777,0.9025501,0.0004020643,0.05058148,0.0002300003],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9878682,0.003910394,0.004325011,0.0009061184,0.002564624,0.0002096931,0.0000616415,0.000005178691,0.0001491014],"genre_scores_gemma":[0.9959605,0.002312263,0.0003958384,0.0007628825,0.0004889783,0.000002276793,0.000005018005,0.00001350679,0.0000587839],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1626074,"threshold_uncertainty_score":0.4111578,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1195586334171882,"score_gpt":0.4688840952086903,"score_spread":0.3493254617915021,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}