{"id":"W2091821514","doi":"10.1021/bi9007066","title":"Stimulation of the Maltose Transporter ATPase by Unliganded Maltose Binding Protein","year":2009,"lang":"en","type":"article","venue":"Biochemistry","topic":"Drug Transport and Resistance Mechanisms","field":"Medicine","cited_by":29,"is_retracted":false,"has_abstract":true,"ca_institutions":"Western University","funders":"National Center for Research Resources","keywords":"Maltose-binding protein; Stimulation; ATPase; Maltose; Transporter; Chemistry; Biochemistry; ATP hydrolysis; Conformational change; Biophysics; Enzyme; Biology; Endocrinology; Fusion protein; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009328711,0.0001397504,0.0001919466,0.00002102566,0.00005254522,0.000005308225,0.0001050486,0.000141118,0.0001268228],"category_scores_gemma":[0.000009794131,0.00009616301,0.0001335841,0.0001622336,0.00005112244,0.00002719446,0.000003782063,0.0001370876,0.000003312214],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003272322,"about_ca_system_score_gemma":0.00007243508,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000002815003,"about_ca_topic_score_gemma":7.307893e-7,"domain_scores_codex":[0.9990725,0.000006685025,0.0002634361,0.0002066454,0.0002687637,0.000181964],"domain_scores_gemma":[0.9994448,0.000004568871,0.0001005688,0.0003158419,0.00004466687,0.00008957052],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001894645,0.000166849,0.001473852,0.0001692123,0.00001525241,0.00001208529,0.00004731265,0.000001189613,0.9969261,0.00002610508,0.0002671221,0.0007054262],"study_design_scores_gemma":[0.001121752,0.00005647761,0.005357706,0.0003097071,0.0000713051,0.000006288403,0.00004549099,0.00002387505,0.9925312,0.00005863255,0.0003091144,0.0001084212],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.997299,0.0001559025,0.0001430516,0.000835614,0.00004498934,0.0003623244,0.00004016193,0.00004086869,0.001078134],"genre_scores_gemma":[0.9915037,0.000007339243,0.0003490905,0.0001071252,0.00005864138,0.000007417289,0.0001038282,0.00001305493,0.007849832],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.006771698,"threshold_uncertainty_score":0.3921414,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.00604867733682387,"score_gpt":0.2236291626623707,"score_spread":0.2175804853255469,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}