{"id":"W2091872525","doi":"10.1182/blood-2011-01-329359","title":"Myeloid dysplasia and bone marrow hypocellularity in adenosine deaminase-deficient severe combined immune deficiency","year":2011,"lang":"en","type":"article","venue":"Blood","topic":"Virus-based gene therapy research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":47,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Saskatchewan; Dalhousie University","funders":"National Institutes of Health","keywords":"Medicine; Bone marrow; Adenosine deaminase; Adenosine deaminase deficiency; Immune system; Dysplasia; Myeloid; Pathology; Immunology; Internal medicine; Adenosine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002714324,0.000265438,0.0002373821,0.000932481,0.0001539609,0.0001739882,0.0001025791,0.0002721455,0.0008661688],"category_scores_gemma":[0.0005815316,0.0001489197,0.00008187957,0.000228966,0.0003104027,0.0001258111,0.0002511123,0.0002826953,0.0001804981],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001547085,"about_ca_system_score_gemma":0.0001225185,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003339884,"about_ca_topic_score_gemma":0.0005652286,"domain_scores_codex":[0.999855,0.00005353461,0.00001737272,0.00002458086,0.00003575917,0.00001363905],"domain_scores_gemma":[0.9997417,0.00005639363,0.000108709,0.00001465042,0.00002334335,0.00005518623],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.006637361,0.0004259436,0.2339538,0.0004934981,0.000127188,0.0420053,0.0004539089,0.0006524567,0.6516512,0.001095391,0.001259582,0.06124438],"study_design_scores_gemma":[0.0003911454,0.005021523,0.6854694,0.0001013089,0.0001689772,0.2301142,0.0002498908,0.00217443,0.0694044,0.001059219,0.005817416,0.00002803422],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.995581,0.001895065,0.0008640196,0.0001060109,0.000006458069,0.00003445403,0.0001016596,0.00003046438,0.001380835],"genre_scores_gemma":[0.998711,0.0004160735,0.000482686,0.00005011351,0.000008543219,0.000007530326,0.00008674459,0.000003828103,0.0002335148],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.000932481,"threshold_uncertainty_score":0.00289762,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01568632805626296,"score_gpt":0.2316180440985172,"score_spread":0.2159317160422543,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}