{"id":"W2091872525","doi":"10.1182/blood-2011-01-329359","title":"Myeloid dysplasia and bone marrow hypocellularity in adenosine deaminase-deficient severe combined immune deficiency","year":2011,"lang":"en","type":"article","venue":"Blood","topic":"Virus-based gene therapy research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":47,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Saskatchewan; Dalhousie University","funders":"National Institutes of Health","keywords":"Medicine; Bone marrow; Adenosine deaminase; Adenosine deaminase deficiency; Immune system; Dysplasia; Myeloid; Pathology; Immunology; Internal medicine; Adenosine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004127537,0.0002041369,0.0002077299,0.0001024561,0.00009097493,0.00002112707,0.0002429473,0.0001731736,0.00007104983],"category_scores_gemma":[0.00005591849,0.0002046418,0.00005909538,0.0001980415,0.0001461758,0.000005073489,0.0002024972,0.0001772359,0.00002096915],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001342665,"about_ca_system_score_gemma":0.00008818314,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00007159185,"about_ca_topic_score_gemma":0.0001916568,"domain_scores_codex":[0.9985304,0.0001124837,0.0002737322,0.000463478,0.0001755262,0.0004443619],"domain_scores_gemma":[0.9992614,0.00001112557,0.00006492406,0.0004811359,0.00006617068,0.0001152718],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001294619,0.001195136,0.02248887,0.00003939105,0.0000289419,0.00005227442,0.000141568,0.00000277737,0.9737947,0.00006206421,0.00004295726,0.0008567251],"study_design_scores_gemma":[0.004100097,0.00421941,0.03918745,0.00002002103,0.00003039001,0.0001133587,0.00009505988,0.00003131921,0.9515622,0.0001474241,0.000169766,0.0003234521],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9902513,0.00768117,0.00002227821,0.00005468976,0.00003981476,0.0003020164,0.00001724099,0.00001752146,0.001613955],"genre_scores_gemma":[0.9987385,0.0003849696,0.0003400227,0.00006269412,0.00002990186,0.00003177181,0.00005542687,0.00003284508,0.0003239255],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02223243,"threshold_uncertainty_score":0.8345051,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01568632805626296,"score_gpt":0.2316180440985172,"score_spread":0.2159317160422543,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}