{"id":"W2091898673","doi":"10.1038/ni1242","title":"Negative regulation of natural killer cell function by EAT-2, a SAP-related adaptor","year":2005,"lang":"en","type":"article","venue":"Nature Immunology","topic":"Immune Cell Function and Interaction","field":"Immunology and Microbiology","cited_by":160,"is_retracted":false,"has_abstract":false,"ca_institutions":"McGill University; Université de Montréal; Montreal Clinical Research Institute","funders":"","keywords":"Signal transducing adaptor protein; Cell biology; Innate immune system; Natural killer cell; Receptor; Biology; Secretion; Function (biology); Phosphorylation; Chemistry; Cytotoxicity; Biochemistry; In vitro","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","research_integrity","insufficient_payload"],"consensus_categories":["insufficient_payload"],"category_scores_codex":[0.0001644946,0.0002739457,0.00037036,0.0002583354,0.0001802521,0.000009243252,0.0001976198,0.001407212,0.003737877],"category_scores_gemma":[0.000112561,0.0002482283,0.0001783097,0.0002889469,0.0002443699,0.0003271026,0.00006097908,0.001713328,0.0009430809],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001483666,"about_ca_system_score_gemma":0.00004688935,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0000582025,"about_ca_topic_score_gemma":0.00001275276,"domain_scores_codex":[0.9983398,0.00029927,0.0005579724,0.0003852255,0.00006016045,0.0003575925],"domain_scores_gemma":[0.9988037,0.0001809973,0.0004193811,0.0003499037,0.0002319507,0.00001406675],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001235378,0.0002039514,0.00006951622,0.000007065387,0.0003058221,2.378879e-7,0.0002687895,0.00001229778,0.885865,0.00117544,0.1057766,0.005079945],"study_design_scores_gemma":[0.002465836,0.000398716,0.006536912,0.00002161766,0.00007070456,0.00004674938,0.0002414127,0.00004434376,0.616401,0.0001186681,0.3734338,0.0002202321],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8691561,0.06663078,0.0004078916,0.002675108,0.03714702,0.0008510833,0.00002467617,0.000436112,0.02267129],"genre_scores_gemma":[0.9207189,0.0001534161,0.0000848955,0.000395153,0.00005752642,0.00001664176,0.0006055016,0.00002688877,0.07794109],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.269464,"threshold_uncertainty_score":0.999997,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.002625083962273588,"score_gpt":0.1992347250869133,"score_spread":0.1966096411246397,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}