{"id":"W2091899323","doi":"10.1172/jci22486","title":"Ikaros integrates endocrine and immune system development","year":2005,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Neuroblastoma Research and Treatments","field":"Medicine","cited_by":51,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto; University Health Network; Ontario Institute for Cancer Research; Sunnybrook Health Science Centre; Health Sciences Centre; Mount Sinai Hospital","funders":"Canadian Institutes of Health Research","keywords":"Immune system; Hormone; Biology; Glucocorticoid; Lymphopoiesis; Endocrine system; Population; Haematopoiesis; Endocrinology; Transcription factor; Immunology; Proopiomelanocortin; Internal medicine; Medicine; Stem cell; Gene; Cell biology; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001728342,0.0003586412,0.0002161742,0.0003815042,0.0002500148,0.0004861729,0.0002577885,0.0001870504,0.002671902],"category_scores_gemma":[0.0001830368,0.0001154732,0.0002214276,0.000159302,0.0003708302,0.0004576358,0.0004221671,0.0005261312,0.001046656],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004197381,"about_ca_system_score_gemma":0.0002980843,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003640535,"about_ca_topic_score_gemma":0.0006098979,"domain_scores_codex":[0.9998003,0.00002105832,0.00001509524,0.00005043637,0.00004277909,0.00007030314],"domain_scores_gemma":[0.9998373,0.000008934502,0.00003807475,0.00001955741,0.00002877746,0.00006746159],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003151681,0.00001897999,0.001456328,0.00004417535,0.000005982236,0.0002060375,0.00004696373,0.0000690161,0.9883329,0.0006340016,0.0002277152,0.008642737],"study_design_scores_gemma":[0.0001004118,0.0004617372,0.05078508,0.00003650492,0.0000887301,0.002422921,0.0003773099,0.001450775,0.9041771,0.001927981,0.03814126,0.00003020635],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9650205,0.007392336,0.01000063,0.0005108221,0.0002428626,0.00003000318,0.001035847,0.001008336,0.01475865],"genre_scores_gemma":[0.9885151,0.001275925,0.002163701,0.00006456001,0.0000516065,0.00001587968,0.0007302185,0.00005218813,0.007130868],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002671902,"threshold_uncertainty_score":0.008938372,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0809858429001423,"score_gpt":0.4030542107000146,"score_spread":0.3220683677998724,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}