{"id":"W2091939983","doi":"10.1016/j.febslet.2007.01.069","title":"RNA interference targeting α8 integrin attenuates smooth muscle cell growth","year":2007,"lang":"en","type":"article","venue":"FEBS Letters","topic":"Cell Adhesion Molecules Research","field":"Medicine","cited_by":20,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University; Université de Montréal; Montreal Clinical Research Institute","funders":"Heart and Stroke Foundation of Canada","keywords":"RHOA; Integrin; Vascular smooth muscle; Gene silencing; Cell biology; RNA interference; Small interfering RNA; Cell growth; Gene knockdown; Cell adhesion; Cell; Chemistry; Biology; Molecular biology; RNA; Signal transduction; Gene; Endocrinology; Biochemistry; Smooth muscle","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006463921,0.0002128506,0.0002561844,0.0002735204,0.00008388963,0.00004353746,0.0002730637,0.00008896094,0.0005341806],"category_scores_gemma":[0.0003056161,0.0001835968,0.0001276544,0.0003488303,0.0001317078,0.00008222578,0.0001790089,0.0006726772,0.0006309612],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001708802,"about_ca_system_score_gemma":0.00004336128,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002219371,"about_ca_topic_score_gemma":0.00001579509,"domain_scores_codex":[0.997995,0.00006012379,0.0003573379,0.0004249042,0.0004902904,0.000672348],"domain_scores_gemma":[0.9989525,0.000221452,0.00008206241,0.000336025,0.0001261775,0.0002818005],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001143566,0.00008315096,0.007958091,0.0001050714,0.00001267388,0.0004159474,0.0003696225,0.000001799776,0.9548631,0.00001797586,0.02895865,0.007099608],"study_design_scores_gemma":[0.001561963,0.0003171561,0.0681351,0.0002247867,0.00003767951,0.00001910006,0.000764566,0.0002245097,0.9047019,0.00003469285,0.02356954,0.0004089714],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9747655,0.0001458508,0.006602423,0.008053266,0.0001993115,0.0002895698,0.000002633845,0.0001122072,0.009829212],"genre_scores_gemma":[0.9889002,0.00002977773,0.003011368,0.006731199,0.0002822555,0.00000852142,0.00002839486,0.00004948421,0.0009588291],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.06017701,"threshold_uncertainty_score":0.810994,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01741170160038177,"score_gpt":0.2730920241227289,"score_spread":0.2556803225223472,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}