{"id":"W2091939983","doi":"10.1016/j.febslet.2007.01.069","title":"RNA interference targeting α8 integrin attenuates smooth muscle cell growth","year":2007,"lang":"en","type":"article","venue":"FEBS Letters","topic":"Cell Adhesion Molecules Research","field":"Medicine","cited_by":20,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University; Université de Montréal; Montreal Clinical Research Institute","funders":"Heart and Stroke Foundation of Canada","keywords":"RHOA; Integrin; Vascular smooth muscle; Gene silencing; Cell biology; RNA interference; Small interfering RNA; Cell growth; Gene knockdown; Cell adhesion; Cell; Chemistry; Biology; Molecular biology; RNA; Signal transduction; Gene; Endocrinology; Biochemistry; Smooth muscle","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001505489,0.0003774281,0.0003253707,0.0002813235,0.0001645684,0.0002812428,0.0001779943,0.0003518411,0.00215977],"category_scores_gemma":[0.0001986006,0.0001775989,0.0002429135,0.0001376649,0.0002801354,0.000133417,0.0001198286,0.000849363,0.0005923505],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002812607,"about_ca_system_score_gemma":0.0002060546,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004881418,"about_ca_topic_score_gemma":0.0005772411,"domain_scores_codex":[0.99979,0.00003514248,0.00001961727,0.00003313537,0.00006066033,0.00006142069],"domain_scores_gemma":[0.9998181,0.00005985475,0.00003900298,0.00002340497,0.0000211506,0.00003855436],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00008732291,0.00003783706,0.00004605625,0.00001205741,0.000003133348,0.00002903252,0.000009529675,0.00001919311,0.9988126,0.0000774513,0.00006742755,0.0007984865],"study_design_scores_gemma":[0.00002685151,0.0004993366,0.001563242,0.000003307919,0.00001521775,0.00009683349,0.00002018323,0.0009904521,0.9951774,0.00005563655,0.001549391,0.000002261644],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9931335,0.001035205,0.002245517,0.0002313349,0.00009331777,0.00002636664,0.0002367699,0.0002327079,0.002765266],"genre_scores_gemma":[0.9908628,0.0008959475,0.002174355,0.0001211022,0.00003212773,0.00006403228,0.0004553319,0.00004976548,0.005344495],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00215977,"threshold_uncertainty_score":0.007225156,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01741170160038177,"score_gpt":0.2730920241227289,"score_spread":0.2556803225223472,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}