{"id":"W2091962088","doi":"10.1038/leu.2012.184","title":"Immunoglobulin gamma heavy chain gene with somatic hypermutation is frequently expressed in acute myeloid leukemia","year":2012,"lang":"en","type":"article","venue":"Leukemia","topic":"Acute Myeloid Leukemia Research","field":"Medicine","cited_by":43,"is_retracted":false,"has_abstract":false,"ca_institutions":"","funders":"University of Texas MD Anderson Cancer Center; University of British Columbia; National Natural Science Foundation of China","keywords":"Somatic hypermutation; Immunoglobulin heavy chain; Myeloid leukemia; Myeloid; Biology; Minimal residual disease; Antibody; Immunoglobulin gene; Haematopoiesis; Cancer research; Immunology; Leukemia; B cell; Stem cell; Genetics","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0007892455,0.0005944762,0.0008850395,0.0005434175,0.0002478016,0.00006509237,0.000446616,0.000439141,0.0004719729],"category_scores_gemma":[0.0001447272,0.0004998983,0.0001747816,0.001073853,0.0002367475,0.0006876008,0.0002330835,0.001135142,0.0005967547],"about_ca_system_candidate":true,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.008308341,"about_ca_system_score_gemma":0.002390356,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001083518,"about_ca_topic_score_gemma":0.00003901962,"domain_scores_codex":[0.9955848,0.0001914882,0.0008310557,0.0007085761,0.001097265,0.001586841],"domain_scores_gemma":[0.9976254,0.0001597914,0.0002455097,0.001167565,0.0002033882,0.0005983262],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.004417957,0.000575029,0.0656286,0.0007048853,0.001003592,0.001289812,0.01543557,0.0005004387,0.8814288,0.0004109224,0.01197711,0.01662728],"study_design_scores_gemma":[0.02649771,0.001774197,0.2072041,0.001222083,0.0007014674,0.002421354,0.001550486,0.01228063,0.7316487,0.0004831393,0.01230442,0.001911681],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9915604,0.001131503,0.0007455227,0.001586071,0.0001755527,0.001395945,0.00005405902,0.0002294102,0.003121514],"genre_scores_gemma":[0.9817637,0.0003486833,0.01008761,0.002098481,0.000517997,0.0003258272,0.0002813261,0.0001655212,0.004410901],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1497801,"threshold_uncertainty_score":0.9997452,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01739420356663057,"score_gpt":0.2744746978745839,"score_spread":0.2570804943079533,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}