{"id":"W2091962088","doi":"10.1038/leu.2012.184","title":"Immunoglobulin gamma heavy chain gene with somatic hypermutation is frequently expressed in acute myeloid leukemia","year":2012,"lang":"en","type":"article","venue":"Leukemia","topic":"Acute Myeloid Leukemia Research","field":"Medicine","cited_by":43,"is_retracted":false,"has_abstract":false,"ca_institutions":"","funders":"University of Texas MD Anderson Cancer Center; University of British Columbia; National Natural Science Foundation of China","keywords":"Somatic hypermutation; Immunoglobulin heavy chain; Myeloid leukemia; Myeloid; Biology; Minimal residual disease; Antibody; Immunoglobulin gene; Haematopoiesis; Cancer research; Immunology; Leukemia; B cell; Stem cell; Genetics","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001462868,0.0001443453,0.0001927502,0.0009109583,0.0003198344,0.0003432668,0.0001922042,0.0004109045,0.00172674],"category_scores_gemma":[0.0004265352,0.0001134861,0.0001567598,0.0006680809,0.0002670697,0.0001552801,0.0002454549,0.0002251614,0.0002910316],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001868185,"about_ca_system_score_gemma":0.0001457551,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004159279,"about_ca_topic_score_gemma":0.0005241458,"domain_scores_codex":[0.9998057,0.00002880951,0.00001959819,0.0000298876,0.00006296549,0.00005311456],"domain_scores_gemma":[0.9997784,0.00005733288,0.00007010838,0.00002158175,0.00003503165,0.00003749326],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.001128929,0.00009331317,0.2223434,0.0001161764,0.0001155356,0.01645034,0.0001909164,0.0002088925,0.7349018,0.0004592227,0.0006387866,0.02335257],"study_design_scores_gemma":[0.0000850285,0.0003418065,0.7856154,0.00002514907,0.000332382,0.08141718,0.0005289863,0.001442789,0.1213453,0.0008168853,0.008030466,0.00001857472],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9974838,0.0005912395,0.000381994,0.00005133553,0.00001159044,0.000007031234,0.00009792695,0.00002006884,0.001354937],"genre_scores_gemma":[0.9990931,0.0002126505,0.0001635417,0.00003108863,0.000013973,0.000003879752,0.0001210917,0.000004444571,0.0003563006],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00172674,"threshold_uncertainty_score":0.005776525,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01739420356663057,"score_gpt":0.2744746978745839,"score_spread":0.2570804943079533,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}