{"id":"W2091965445","doi":"10.1139/o00-006","title":"Proteasome from cytokine-treated human cells shows stimulated BrAAP activity and depressed PGPH activity","year":2000,"lang":"en","type":"article","venue":"Biochemistry and Cell Biology","topic":"Ubiquitin and proteasome pathways","field":"Biochemistry, Genetics and Molecular Biology","cited_by":7,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"","keywords":"Tumor necrosis factor alpha; Umbilical vein; Proteasome; Cytokine; Interferon gamma; Amino acid; Peptide; Interferon; Interleukin; Biology; Lipopolysaccharide; Molecular biology; Biochemistry; Chemistry; Endocrinology; Internal medicine; Immunology; In vitro; Medicine","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":true,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001283805,0.0004344861,0.0003409584,0.0001942354,0.0001286149,0.0003079324,0.00009392701,0.0001878032,0.002034617],"category_scores_gemma":[0.0002243413,0.0001206858,0.0002007192,0.0001752289,0.0001409921,0.0001555083,0.0001387676,0.0004270785,0.001109926],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001861998,"about_ca_system_score_gemma":0.0001287127,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004163395,"about_ca_topic_score_gemma":0.0003336616,"domain_scores_codex":[0.9998461,0.00001731086,0.00001544676,0.00004122705,0.00004160432,0.00003819655],"domain_scores_gemma":[0.9998579,0.00002586496,0.00002950679,0.00002407787,0.0000238006,0.0000387322],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001272466,0.00001137344,0.000354089,0.00004133713,0.000007291471,0.00009355512,0.00001619758,0.000009801992,0.9981028,0.00002329578,0.00003672354,0.001176293],"study_design_scores_gemma":[0.00001312516,0.0001923262,0.01215977,0.000006001451,0.00001511586,0.001206401,0.00002537538,0.0001836886,0.9836282,0.00005178651,0.00251336,0.000004972456],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.981777,0.009239403,0.004559518,0.0001727183,0.0001103151,0.00003543472,0.001467041,0.0001210117,0.002517413],"genre_scores_gemma":[0.9877446,0.002070388,0.002801617,0.00007546673,0.00004952931,0.00003751999,0.003949753,0.00002517983,0.003245816],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002034617,"threshold_uncertainty_score":0.006806433,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01027546189729891,"score_gpt":0.2345549663401198,"score_spread":0.2242795044428209,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}