{"id":"W2092012527","doi":"10.1039/c3cp52621f","title":"Transfection and structural properties of phytanyl substituted gemini surfactant-based vectors for gene delivery","year":2013,"lang":"en","type":"article","venue":"Physical Chemistry Chemical Physics","topic":"RNA Interference and Gene Delivery","field":"Biochemistry, Genetics and Molecular Biology","cited_by":37,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Waterloo","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research","keywords":"Transfection; Zeta potential; Small-angle X-ray scattering; Cytotoxicity; Gene delivery; Pulmonary surfactant; Chemistry; Scattering; Surface charge; Particle size; Cationic polymerization; Biophysics; Particle (ecology); In vitro; Materials science; Nanotechnology; Nanoparticle; Physics; Physical chemistry; Organic chemistry; Biochemistry; Optics; Gene; Biology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003087372,0.0002477286,0.000220314,0.0001831929,0.0001320713,0.0003451142,0.0001326494,0.0002645968,0.00019834],"category_scores_gemma":[0.0004173715,0.0000936236,0.0001675915,0.0002182167,0.0001827071,0.0003096348,0.0001285609,0.0002686347,0.0001265853],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003796145,"about_ca_system_score_gemma":0.0002290511,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005804869,"about_ca_topic_score_gemma":0.0009154528,"domain_scores_codex":[0.9998302,0.00004674731,0.00002060206,0.00002390321,0.00006390033,0.0000145786],"domain_scores_gemma":[0.999835,0.00003732345,0.00004790914,0.00001037241,0.00005461793,0.00001471943],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00002213188,0.000004185739,0.0001289348,0.00002338178,0.000002606923,0.00001908065,0.00001371136,0.00009511031,0.9986772,0.00005304272,0.000005302302,0.00095525],"study_design_scores_gemma":[0.000001780152,0.00009264394,0.0007809024,0.000001977976,0.00001238663,0.0001096988,0.00001270695,0.0009366652,0.9973143,0.00002349372,0.0007103556,0.000003076309],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9875906,0.002247955,0.009151649,0.0000855777,0.00001271086,0.00003335504,0.00009742562,0.00004149677,0.0007392151],"genre_scores_gemma":[0.9886301,0.002011368,0.007930152,0.00004079915,0.000006050439,0.00003206671,0.0002484484,0.00002201006,0.001079097],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0005804869,"threshold_uncertainty_score":0.002754271,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0128098367303069,"score_gpt":0.216084655585722,"score_spread":0.2032748188554152,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}