{"id":"W2092012527","doi":"10.1039/c3cp52621f","title":"Transfection and structural properties of phytanyl substituted gemini surfactant-based vectors for gene delivery","year":2013,"lang":"en","type":"article","venue":"Physical Chemistry Chemical Physics","topic":"RNA Interference and Gene Delivery","field":"Biochemistry, Genetics and Molecular Biology","cited_by":37,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Waterloo","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research","keywords":"Transfection; Zeta potential; Small-angle X-ray scattering; Cytotoxicity; Gene delivery; Pulmonary surfactant; Chemistry; Scattering; Surface charge; Particle size; Cationic polymerization; Biophysics; Particle (ecology); In vitro; Materials science; Nanotechnology; Nanoparticle; Physics; Physical chemistry; Organic chemistry; Biochemistry; Optics; Gene; Biology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00002514944,0.0002499928,0.0002785988,0.000006757139,0.00004789424,0.00002266581,0.0001618526,0.000136462,0.000007353119],"category_scores_gemma":[0.00003363942,0.0002226069,0.0001913515,0.00007079147,0.000233909,0.00001724442,0.00004239093,0.0001114078,0.000002103884],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001791353,"about_ca_system_score_gemma":0.00005505936,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00003093778,"about_ca_topic_score_gemma":4.373488e-7,"domain_scores_codex":[0.9989711,0.00001044019,0.0002107368,0.0004014804,0.0001344463,0.0002717708],"domain_scores_gemma":[0.9993243,0.00002300707,0.00008272946,0.0002436822,0.0002226983,0.0001035815],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001610434,0.0001070795,0.0001349634,0.0002294819,0.00006530567,1.579467e-7,0.00003544599,0.0001105249,0.9980454,0.000004206202,0.00008878075,0.001017602],"study_design_scores_gemma":[0.0006111219,0.00008095223,0.0001404165,0.00003164809,0.00004720581,0.000001878151,0.00002189721,0.004684297,0.9937699,0.0003112092,0.00002571305,0.0002736898],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9988241,0.0001563585,0.0005674041,0.00002856036,0.00003485268,0.0002495096,0.00006418351,0.00001994801,0.00005511217],"genre_scores_gemma":[0.9989467,0.00001385927,0.0002058427,0.00003689319,0.0004504794,0.0000730814,0.0002226993,0.00002733007,0.0000231082],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004573772,"threshold_uncertainty_score":0.9077644,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0128098367303069,"score_gpt":0.216084655585722,"score_spread":0.2032748188554152,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}