{"id":"W2092015085","doi":"10.1016/j.cellsig.2012.10.011","title":"TGF-beta inhibits human cutaneous melanoma cell migration and invasion through regulation of the plasminogen activator system","year":2012,"lang":"en","type":"article","venue":"Cellular Signalling","topic":"Protease and Inhibitor Mechanisms","field":"Biochemistry, Genetics and Molecular Biology","cited_by":30,"is_retracted":false,"has_abstract":false,"ca_institutions":"McGill University Health Centre","funders":"Canadian Institutes of Health Research; U.S. Bureau of Land Management","keywords":"Melanoma; Cancer research; Cell migration; Metastasis; Plasmin; Plasminogen activator; Tumor progression; Cancer; SMAD; Transforming growth factor; Medicine; Cell; Biology; Internal medicine","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001025434,0.0001919661,0.0001413988,0.0001408589,0.0001057402,0.0001936558,0.00009636146,0.00009961188,0.001247248],"category_scores_gemma":[0.00009523257,0.00007869232,0.0001415802,0.00009223141,0.0001168683,0.0000625109,0.00007977008,0.0004061859,0.0002840193],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001150798,"about_ca_system_score_gemma":0.0001600152,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009110182,"about_ca_topic_score_gemma":0.001179428,"domain_scores_codex":[0.9999232,0.00002416106,0.000004868737,0.000004302845,0.00001325498,0.00003014262],"domain_scores_gemma":[0.9999641,0.00001196042,0.000005718087,0.000004988312,0.000003617609,0.000009659598],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0007165229,0.0001363414,0.0004280568,0.00004541532,0.000009689594,0.00008539534,0.00001994568,0.0000783244,0.993059,0.00007713575,0.0001510239,0.005193022],"study_design_scores_gemma":[0.0001896167,0.001698054,0.01316033,0.00001028532,0.00004845532,0.0004248785,0.00004875239,0.001124787,0.9789048,0.00007405695,0.004310634,0.00000545387],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9920378,0.00378403,0.000644204,0.0001436455,0.00004437949,0.00001760884,0.0001049209,0.00005010439,0.003173296],"genre_scores_gemma":[0.9954249,0.001715219,0.0002779051,0.0000405791,0.00001580091,0.00001593529,0.0001399027,0.000007280908,0.00236248],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001247248,"threshold_uncertainty_score":0.004172504,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01380844299855609,"score_gpt":0.2045105811835345,"score_spread":0.1907021381849784,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}