{"id":"W2092032893","doi":"10.1021/bi701962c","title":"Role of Phospholipid Scramblase 3 in the Regulation of Tumor Necrosis Factor-α-Induced Apoptosis","year":2008,"lang":"en","type":"article","venue":"Biochemistry","topic":"Cell death mechanisms and regulation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":60,"is_retracted":false,"has_abstract":true,"ca_institutions":"McMaster University","funders":"","keywords":"Cardiolipin; Phospholipid scramblase; Cytochrome c; Apoptosis; Downregulation and upregulation; Cell biology; Mitochondrion; Tumor necrosis factor alpha; Chemistry; Biology; Phospholipid; Phosphatidylserine; Biochemistry; Endocrinology; Membrane","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001005066,0.0001193784,0.0001403802,0.00002687388,0.0000416985,0.000004041744,0.0001747439,0.0001465859,0.00002533423],"category_scores_gemma":[0.00004409674,0.00009617655,0.000103141,0.0001350069,0.00006978359,0.00000316127,0.00004264256,0.00005720745,9.505973e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001148576,"about_ca_system_score_gemma":0.00006185788,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00007246923,"about_ca_topic_score_gemma":0.000003431059,"domain_scores_codex":[0.9991837,0.00002588473,0.0002687698,0.0002143114,0.0001737036,0.0001336139],"domain_scores_gemma":[0.9993391,0.00001024487,0.0001686439,0.0003773122,0.00007384059,0.00003085329],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00005271087,0.00009535079,0.001323184,0.0000316611,0.00001085198,2.354424e-7,0.0001117105,0.00001411431,0.9973586,0.00002260763,0.00010637,0.0008726166],"study_design_scores_gemma":[0.0003318188,0.00007337701,0.02140661,0.00001881554,0.000008319269,0.00001044869,0.0001422648,0.00008728636,0.9775423,0.00006328262,0.0002127384,0.0001027616],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9988998,0.0002799826,0.00003094857,0.00002381627,0.0000367861,0.0001252695,0.0000205126,0.000004178139,0.0005786728],"genre_scores_gemma":[0.9993202,0.0000698176,0.0002282843,0.00002908098,0.00007936191,0.00001196206,0.00009416058,0.00001151178,0.000155591],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02008343,"threshold_uncertainty_score":0.3921966,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01143011582947484,"score_gpt":0.2212465550270106,"score_spread":0.2098164391975358,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}