{"id":"W2092076919","doi":"10.1016/s0882-4010(02)00194-8","title":"Mice intradermally-inoculated with the intact lipopolysaccharide, but not the lipid A or O-chain, from Francisella tularensis LVS rapidly acquire varying degrees of enhanced resistance against systemic or aerogenic challenge with virulent strains of the pathogen","year":2003,"lang":"en","type":"article","venue":"Microbial Pathogenesis","topic":"Bacillus and Francisella bacterial research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":34,"is_retracted":false,"has_abstract":false,"ca_institutions":"National Research Council Canada; Institute for Biological Sciences","funders":"National Institute of Allergy and Infectious Diseases","keywords":"Francisella tularensis; Lipopolysaccharide; Microbiology; Pathogen; Virulence; Lipid A; Francisella; Tularemia; Biology; Intracellular; Virology; Immunology; Biochemistry; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004786524,0.001236397,0.0008186427,0.001008945,0.0003054424,0.0005276109,0.0003733957,0.001076716,0.002088234],"category_scores_gemma":[0.0003426405,0.0004385432,0.0005298844,0.0002788172,0.0007771971,0.0009428292,0.0003432063,0.002793435,0.0009247455],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004013006,"about_ca_system_score_gemma":0.0003129289,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006038078,"about_ca_topic_score_gemma":0.0005567277,"domain_scores_codex":[0.999481,0.00004591378,0.00003227716,0.0001127504,0.0001002581,0.0002277911],"domain_scores_gemma":[0.9991004,0.0002024851,0.0002459495,0.0001336594,0.00005356036,0.0002638889],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001027688,0.0003710683,0.0003005349,0.00003461649,0.00001276777,0.00008257125,0.00004560565,0.00007029504,0.9969537,0.000159011,0.00006518525,0.0008769925],"study_design_scores_gemma":[0.0001100526,0.005452578,0.004478644,0.00002139156,0.00004262348,0.0003919594,0.00007396838,0.000979508,0.9870268,0.0002122667,0.001191047,0.00001923057],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9926981,0.0008032411,0.003329316,0.0001873284,0.0001853967,0.00008549922,0.0006128858,0.0003465428,0.001751543],"genre_scores_gemma":[0.9882033,0.0006139033,0.002545209,0.0002044789,0.00008713231,0.00009611245,0.001295413,0.00007828805,0.006876149],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002088234,"threshold_uncertainty_score":0.006985784,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01357820499612002,"score_gpt":0.2144653969963048,"score_spread":0.2008871920001848,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}