{"id":"W2092130790","doi":"10.1517/14728214.2010.517746","title":"Emerging therapies for cystic fibrosis lung disease","year":2010,"lang":"en","type":"review","venue":"Expert Opinion on Emerging Drugs","topic":"Cystic Fibrosis Research Advances","field":"Medicine","cited_by":32,"is_retracted":false,"has_abstract":true,"ca_institutions":"Hospital for Sick Children; SickKids Foundation; University of Toronto","funders":"","keywords":"Cystic fibrosis; Mucociliary clearance; Medicine; Chloride channel; Airway; Lung; Cystic fibrosis transmembrane conductance regulator; Fibrosis; Respiratory system; Lung disease; Ion channel; Pathology; Internal medicine; Receptor; Cell biology; Anesthesia; Biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0005282112,0.0009727627,0.002216793,0.0007632134,0.0004480573,0.0001195784,0.0005456067,0.000352077,0.0004177254],"category_scores_gemma":[0.001409658,0.0007586529,0.001363522,0.0005479359,0.0001987847,0.000183624,0.0001694162,0.001017346,0.0001219958],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000347087,"about_ca_system_score_gemma":0.0006544638,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001920545,"about_ca_topic_score_gemma":7.545345e-7,"domain_scores_codex":[0.995364,0.0001943694,0.001032231,0.001237078,0.001122708,0.001049664],"domain_scores_gemma":[0.9958069,0.001455812,0.0004344636,0.001318095,0.0002187728,0.0007659672],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0003174247,0.0001776497,0.000002744006,0.01468894,0.0002511217,0.000009213845,0.0005811214,0.000002638589,0.00003658132,0.0004091241,0.01985875,0.9636647],"study_design_scores_gemma":[0.0008683655,0.0002013353,0.000006021119,0.03340176,0.0001450928,0.00001252413,0.0001621872,0.0005962377,0.000009757689,0.00006685383,0.9638249,0.0007049803],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.000002704913,0.9901006,0.001266276,0.001504482,0.003073286,0.003190983,0.0002415488,0.0003163553,0.0003037743],"genre_scores_gemma":[0.00001776971,0.9863099,0.005452945,0.0002563493,0.002888283,0.002352606,0.00127108,0.0003261596,0.001124853],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9629597,"threshold_uncertainty_score":0.9994864,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03499504691110344,"score_gpt":0.4096748499475913,"score_spread":0.3746798030364878,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}