{"id":"W2092130790","doi":"10.1517/14728214.2010.517746","title":"Emerging therapies for cystic fibrosis lung disease","year":2010,"lang":"en","type":"review","venue":"Expert Opinion on Emerging Drugs","topic":"Cystic Fibrosis Research Advances","field":"Medicine","cited_by":32,"is_retracted":false,"has_abstract":true,"ca_institutions":"Hospital for Sick Children; SickKids Foundation; University of Toronto","funders":"","keywords":"Cystic fibrosis; Mucociliary clearance; Medicine; Chloride channel; Airway; Lung; Cystic fibrosis transmembrane conductance regulator; Fibrosis; Respiratory system; Lung disease; Ion channel; Pathology; Internal medicine; Receptor; Cell biology; Anesthesia; Biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006029705,0.0009589868,0.001129295,0.001640836,0.0003136742,0.0007096945,0.000687138,0.001500844,0.007544317],"category_scores_gemma":[0.000534239,0.0001777575,0.0005144473,0.001165366,0.0004272839,0.001343564,0.000683252,0.002572661,0.004998344],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000623774,"about_ca_system_score_gemma":0.0008739209,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006767623,"about_ca_topic_score_gemma":0.001642797,"domain_scores_codex":[0.9997491,0.00004554177,0.0000241297,0.00003115397,0.0001288131,0.00002126239],"domain_scores_gemma":[0.9997736,0.00008266656,0.00003034568,0.000009284267,0.00007478707,0.00002927646],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0000691015,0.0001005367,0.00009621015,0.007379746,0.0000658151,0.0003411693,0.00006547642,0.0002333606,0.003281658,0.005135344,0.07592572,0.9073059],"study_design_scores_gemma":[0.00003196561,0.00007434098,0.0003321272,0.00182001,0.00004447017,0.0009446096,0.00003627882,0.00006274794,0.0003218191,0.001786318,0.9945363,0.000009151176],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0001352571,0.9944465,0.0002742585,0.001222803,0.0008384814,0.00001446911,0.00002251193,0.00001677395,0.003028985],"genre_scores_gemma":[0.0006909684,0.9946018,0.0006370457,0.0009505365,0.0005553546,0.00001724387,0.00004718218,0.000002830996,0.002497085],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.007544317,"threshold_uncertainty_score":0.02523822,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03499504691110344,"score_gpt":0.4096748499475913,"score_spread":0.3746798030364878,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}