{"id":"W2092153840","doi":"10.1016/j.molbiopara.2003.10.020","title":"In vivo transcription analysis utilizing chromatin immunoprecipation reveals a role for trypanosome transcription factor PBP-1 in RNA polymerase III-dependent transcription","year":2003,"lang":"en","type":"article","venue":"Molecular and Biochemical Parasitology","topic":"Trypanosoma species research and implications","field":"Medicine","cited_by":6,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Toronto","funders":"National Institute of Allergy and Infectious Diseases; National Institutes of Health; American Heart Association","keywords":"Biology; Promoter; RNA polymerase II; Transcription factor II D; Molecular biology; Transcription (linguistics); Small nuclear RNA; General transcription factor; Transcription preinitiation complex; RNA; RNA polymerase II holoenzyme; Transcription factor II A; Chromatin immunoprecipitation; Transcription factor II F; Response element; Genetics; Gene; Gene expression; Non-coding RNA","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000281674,0.0005222455,0.0003760699,0.000487912,0.0005291089,0.0008435537,0.0005584494,0.0003947956,0.003598369],"category_scores_gemma":[0.0003085901,0.0003940631,0.0006119439,0.0002940278,0.0006658219,0.0003806973,0.0003298966,0.001833716,0.001332255],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006810419,"about_ca_system_score_gemma":0.0003351881,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001294525,"about_ca_topic_score_gemma":0.003278374,"domain_scores_codex":[0.9997752,0.00003281037,0.00001385552,0.00007413785,0.00004295061,0.00006107948],"domain_scores_gemma":[0.9996719,0.0001517503,0.00004108753,0.00004400756,0.00003192709,0.000059227],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00009686488,0.00002787544,0.0003264778,0.00002976559,0.000006362172,0.00004555089,0.00002045228,0.00003251865,0.9983009,0.0002371024,0.00005421205,0.000822071],"study_design_scores_gemma":[0.00001165125,0.00005470724,0.003017609,0.000005612598,0.00001651378,0.0001846024,0.00003342248,0.0007722705,0.9946635,0.0001753108,0.001060756,0.000004120229],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9317203,0.004801123,0.05558287,0.0009832643,0.0002539285,0.00006858565,0.001727865,0.0004352766,0.004426749],"genre_scores_gemma":[0.9769768,0.0009721905,0.01360623,0.0002603587,0.00008482933,0.00004942161,0.003616704,0.0001212134,0.004312282],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003598369,"threshold_uncertainty_score":0.01203769,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01836923110421197,"score_gpt":0.3212418014840774,"score_spread":0.3028725703798654,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}