{"id":"W2092171739","doi":"10.1074/jbc.m401800200","title":"RGS17/RGSZ2, a Novel Regulator of Gi/o, Gz, and Gq Signaling","year":2004,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Protein Kinase Regulation and GTPase Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":96,"is_retracted":false,"has_abstract":true,"ca_institutions":"Western University; University of Ottawa","funders":"","keywords":"G protein; Regulator of G protein signaling; GTPase-activating protein; Gq alpha subunit; GTPase; Cell biology; Immunoprecipitation; Biology; Signal transduction; G protein-coupled receptor; Molecular biology; Biochemistry; Chemistry; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003131045,0.0001399554,0.000257358,0.00002315059,0.00004184146,0.00001326836,0.0001490182,0.0002604842,0.00004984817],"category_scores_gemma":[0.0002332073,0.0001047868,0.0001569286,0.00007267196,0.0001714715,0.000005320273,0.00007449903,0.0001492513,5.575216e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001782782,"about_ca_system_score_gemma":0.0000909286,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000001706834,"about_ca_topic_score_gemma":1.596287e-7,"domain_scores_codex":[0.9990469,0.00001673125,0.0004524311,0.0001792699,0.0001461567,0.0001585401],"domain_scores_gemma":[0.9991328,0.00001586577,0.0003972112,0.0001349006,0.0001868082,0.0001323868],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001428672,0.00009464153,0.0005431424,0.00004172259,0.00004484146,0.000008600968,0.00001288824,0.0002472103,0.9982967,0.00007961085,0.00002028755,0.0004674266],"study_design_scores_gemma":[0.001137499,0.0002440571,0.0008569854,0.0000915793,0.00001812895,0.0002717887,0.00006194942,0.000007128907,0.9943501,0.0005436385,0.002285079,0.0001320035],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9937592,0.001734702,0.004072454,0.0001304765,0.00003238968,0.00005213582,0.00001063184,0.000004626602,0.0002033615],"genre_scores_gemma":[0.9943811,0.000128782,0.005036678,0.0000837706,0.0003029246,0.000001407402,0.00001154585,0.000008550187,0.00004528653],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003946598,"threshold_uncertainty_score":0.427308,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01832075137006898,"score_gpt":0.2450097893136413,"score_spread":0.2266890379435723,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}