{"id":"W2092351149","doi":"10.1073/pnas.0909529106","title":"Predicted poxvirus FEN1-like nuclease required for homologous recombination, double-strand break repair and full-size genome formation","year":2009,"lang":"en","type":"article","venue":"Proceedings of the National Academy of Sciences","topic":"Poxvirus research and outbreaks","field":"Immunology and Microbiology","cited_by":48,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"National Institute of Allergy and Infectious Diseases; NHLBI Division of Intramural Research; National Institutes of Health; University of Alberta; Division of Intramural Research, National Institute of Allergy and Infectious Diseases","keywords":"Biology; Vaccinia; Homologous recombination; Genome; DNA replication; DNA; Genetics; Viral replication; Virus; Molecular biology; Virology; Gene; Recombinant DNA","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001342048,0.000113029,0.0001906859,0.000177484,0.0004319366,0.0000246882,0.0004809814,0.0001874393,0.00002709426],"category_scores_gemma":[0.0006265612,0.00008064383,0.00009329286,0.0003906001,0.0008236369,0.0006674044,0.00006971648,0.0001736685,0.000002632179],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00004135669,"about_ca_system_score_gemma":0.00004720459,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000008393593,"about_ca_topic_score_gemma":3.211957e-7,"domain_scores_codex":[0.998815,0.00001546753,0.000397978,0.0002600387,0.0002443036,0.0002672108],"domain_scores_gemma":[0.9989997,0.0001823395,0.0003552928,0.00001398387,0.0004147493,0.00003396458],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0006865706,0.00009250076,0.0002150054,0.00006239698,0.00003894296,1.279369e-8,0.0003107678,0.000005135578,0.9810366,0.01287069,0.003264245,0.001417114],"study_design_scores_gemma":[0.007131587,0.001585003,0.2117625,0.0001670279,0.00008875638,0.0002554163,0.0004482463,0.0005333076,0.6575066,0.1119894,0.008148645,0.0003834559],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9920244,0.0006955626,0.000004455362,0.003815898,0.00004176724,0.0006247152,0.000137715,0.00005001539,0.002605438],"genre_scores_gemma":[0.9984507,0.0001180551,0.0005251023,0.0003260734,0.00002811548,0.00002070935,0.000004084444,0.000003711741,0.0005234444],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.32353,"threshold_uncertainty_score":0.3322151,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03450191930767806,"score_gpt":0.2947745800666355,"score_spread":0.2602726607589575,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}