{"id":"W2092396761","doi":"10.1081/ncn-100002449","title":"INHIBITION OF<i>IN VITRO</i>PRE-mRNA SPLICING IN<i>S. CEREVISIAE</i>BY BRANCHED OLIGONUCLEOTIDES","year":2001,"lang":"en","type":"article","venue":"Nucleosides Nucleotides & Nucleic Acids","topic":"RNA Research and Splicing","field":"Biochemistry, Genetics and Molecular Biology","cited_by":5,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto; Western University; McGill University","funders":"","keywords":"RNA splicing; Nucleic acid; Oligonucleotide; RNA; Messenger RNA; Precursor mRNA; In vitro; Saccharomyces cerevisiae; Chemistry; Yeast; Biochemistry; Biology; Molecular biology; Cell biology; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001721382,0.0004187266,0.0002130756,0.00009001425,0.00009038367,0.0003173106,0.0001630624,0.0002115864,0.0007632482],"category_scores_gemma":[0.0002889139,0.0001375643,0.0002592326,0.0001120182,0.0001516301,0.0001122764,0.0001313547,0.0003837155,0.0003371668],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002257009,"about_ca_system_score_gemma":0.0001642368,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004953577,"about_ca_topic_score_gemma":0.000656748,"domain_scores_codex":[0.9998367,0.00005062418,0.00002205715,0.00003025749,0.00003392044,0.00002642762],"domain_scores_gemma":[0.9997506,0.00006968422,0.00007127315,0.00002350467,0.00003887476,0.00004609497],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001262037,0.00001922185,0.00007869671,0.00003853715,0.000006933654,0.00003004535,0.00001015657,0.0001458783,0.9982917,0.0001008252,0.00001771652,0.001134178],"study_design_scores_gemma":[0.000006895298,0.0001702064,0.0002625883,0.00000394359,0.000006660819,0.00003568173,0.000007785615,0.000330995,0.9985148,0.00002091137,0.000637262,0.000002281909],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9919891,0.002011428,0.003766394,0.00005512358,0.00004352063,0.00003302225,0.0001938125,0.00007910137,0.001828448],"genre_scores_gemma":[0.9897628,0.001851494,0.005982588,0.00007175771,0.00001460189,0.00004668366,0.0005403743,0.00004661617,0.00168299],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0007632482,"threshold_uncertainty_score":0.002553284,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008061444833484992,"score_gpt":0.249551984973136,"score_spread":0.241490540139651,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}