{"id":"W2092436669","doi":"10.3390/molecules20046959","title":"Kinugasa Reactions in Water: From Green Chemistry to Bioorthogonal Labelling","year":2015,"lang":"en","type":"review","venue":"Molecules","topic":"Click Chemistry and Applications","field":"Chemistry","cited_by":25,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Ottawa; National Research Council Canada","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Bioorthogonal chemistry; Chemistry; Labelling; Aqueous medium; Combinatorial chemistry; Aqueous solution; Green chemistry; Scope (computer science); Organic chemistry; Reaction mechanism; Catalysis; Click chemistry; Computer science; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003221713,0.000739308,0.0006478081,0.001390865,0.0001937677,0.0006133371,0.0004599221,0.0006514113,0.001719196],"category_scores_gemma":[0.000214789,0.00034427,0.0002820765,0.001096254,0.0003351082,0.0009509755,0.0005653627,0.001281379,0.001314116],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005306317,"about_ca_system_score_gemma":0.0004058022,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005898491,"about_ca_topic_score_gemma":0.001167744,"domain_scores_codex":[0.9998883,0.00001437232,0.000009291357,0.00002320659,0.00004367563,0.00002123892],"domain_scores_gemma":[0.9999474,0.00001774351,0.00001160717,0.000002691323,0.00001318438,0.000007316296],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00006880097,0.0001254469,0.000165192,0.01336628,0.00007016277,0.0005645961,0.0001731533,0.001061694,0.08577464,0.02276397,0.01516442,0.8607016],"study_design_scores_gemma":[0.00001138752,0.0001639553,0.0003777244,0.0006417742,0.00004533749,0.001196002,0.00005114503,0.0003094555,0.03017938,0.002239547,0.964756,0.00002832422],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.001889676,0.9907081,0.002131072,0.0002225486,0.0002249161,0.00001738696,0.00003071357,0.00004194857,0.004733551],"genre_scores_gemma":[0.01096344,0.9829921,0.001454196,0.0001712247,0.000108068,0.00002495066,0.00005196827,0.000007062943,0.004227021],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.001719196,"threshold_uncertainty_score":0.005751312,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.06406770193040126,"score_gpt":0.3269185192524581,"score_spread":0.2628508173220568,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}