{"id":"W2092604129","doi":"10.1074/jbc.m111.307124","title":"Macrophage Mesenchymal Migration Requires Podosome Stabilization by Filamin A","year":2012,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Cellular Mechanics and Interactions","field":"Biochemistry, Genetics and Molecular Biology","cited_by":82,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"National Institute of General Medical Sciences; University of California, San Francisco; Fondation pour la Recherche Médicale; Sidaction; National Institutes of Health; Agence Nationale de la Recherche","keywords":"Podosome; Filamin; Cell biology; FLNA; Cell migration; Invadopodia; Actin; Biology; Cytoskeleton; Cell; Cancer cell; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002577539,0.0001129651,0.0001345589,0.00001369872,0.00004783472,0.00001892238,0.0001334856,0.0002147814,0.0003159869],"category_scores_gemma":[0.0002795056,0.0000841317,0.000137178,0.00005797661,0.00003649472,0.00001372156,0.00005005029,0.0001491446,0.000004553887],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002613182,"about_ca_system_score_gemma":0.00002587679,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000001783114,"about_ca_topic_score_gemma":4.444182e-7,"domain_scores_codex":[0.9992036,0.00004311111,0.000326321,0.0001180244,0.0001164662,0.000192433],"domain_scores_gemma":[0.9993538,0.00001661547,0.0002542898,0.0001253986,0.0001190215,0.0001308887],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00005851381,0.0001493634,0.001676928,0.000008183174,0.00002490095,0.000001686249,0.00001435408,0.000002877935,0.9917793,0.00001332242,0.005841921,0.0004286144],"study_design_scores_gemma":[0.00019608,0.0001944137,0.0003660659,0.000008575148,0.00001116582,0.000120779,0.00008021895,0.00002887585,0.9229732,0.00003547554,0.07588398,0.0001012369],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9937267,0.002699688,0.002675049,0.0001559192,0.0001842505,0.00003943574,0.00002455545,0.000004423364,0.0004900227],"genre_scores_gemma":[0.9975508,0.0006370949,0.000340402,0.00009210721,0.0006350714,0.000002498849,0.0001647638,0.000008415522,0.0005687755],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.07004206,"threshold_uncertainty_score":0.3459835,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01546742743200119,"score_gpt":0.2558840143372413,"score_spread":0.2404165869052401,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}