{"id":"W2092636994","doi":"10.1016/j.molstruc.2007.07.043","title":"Study of interaction of spironolactone with hydroxypropyl-β-cyclodextrin in aqueous solution and in solid state","year":2007,"lang":"en","type":"article","venue":"Journal of Molecular Structure","topic":"Drug Solubulity and Delivery Systems","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":25,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of British Columbia","funders":"","keywords":"Chemistry; Aqueous solution; Fourier transform infrared spectroscopy; Hydrogen bond; Differential scanning calorimetry; Stoichiometry; Raman spectroscopy; Cyclodextrin; Solubility; Infrared spectroscopy; Physical chemistry; Crystallography; Molecule; Organic chemistry; Chemical engineering; Thermodynamics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0008455356,0.000133247,0.0004051896,0.0003806234,0.00002136765,0.000005429747,0.0001108454,0.0001553203,0.0000189028],"category_scores_gemma":[0.00003549162,0.0001091889,0.00004157644,0.0002021427,0.00007448354,0.0001351113,0.00003118264,0.0007645697,1.8343e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00007810098,"about_ca_system_score_gemma":0.00005527636,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001329609,"about_ca_topic_score_gemma":0.001330967,"domain_scores_codex":[0.9983664,0.0003296907,0.0007754599,0.0001254849,0.0002137953,0.0001891809],"domain_scores_gemma":[0.9989539,0.00008584544,0.0006623564,0.00009303633,0.0001264072,0.00007846024],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.007736053,0.0009962142,0.3254651,0.0001806553,0.0003090613,0.001482627,0.00873962,0.03830632,0.6011171,0.00001168091,0.00001592887,0.01563967],"study_design_scores_gemma":[0.01474874,0.004084631,0.4326694,0.0003234614,0.0002576327,0.001343049,0.006317161,0.002662261,0.536326,0.0004939408,0.0003888303,0.0003848813],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.998298,0.00064049,0.000399112,0.00003669106,0.0002401566,0.0002850347,0.00000616251,0.000002536693,0.0000917993],"genre_scores_gemma":[0.9997272,0.00004768572,0.0001317599,0.00004384911,0.00002945846,6.829846e-7,9.446366e-7,0.000009799584,0.000008650044],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1072043,"threshold_uncertainty_score":0.4452595,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03480806719638299,"score_gpt":0.3870009997429082,"score_spread":0.3521929325465253,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}