{"id":"W2092690841","doi":"10.1021/np200689w","title":"Jadomycins Derived from the Assimilation and Incorporation of Norvaline and Norleucine","year":2011,"lang":"en","type":"article","venue":"Journal of Natural Products","topic":"Microbial Natural Products and Biosynthesis","field":"Medicine","cited_by":29,"is_retracted":false,"has_abstract":true,"ca_institutions":"Institute for Marine Biosciences; Acadia University; Dalhousie University","funders":"","keywords":"Norvaline; Norleucine; Biochemistry; Biology; Amino acid; Cytotoxicity; Antimicrobial; Chemistry; Stereochemistry; Bacteria; In vitro; Microbiology; Valine; Leucine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00007861566,0.0003675966,0.0002031358,0.0002540132,0.0001443797,0.0002985958,0.0001509337,0.0001336651,0.0006019627],"category_scores_gemma":[0.0001557685,0.00008117707,0.0001335881,0.0002621133,0.0001526305,0.000131765,0.0001873571,0.0004151543,0.0002026806],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002597197,"about_ca_system_score_gemma":0.000258709,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006823764,"about_ca_topic_score_gemma":0.001866381,"domain_scores_codex":[0.999926,0.00001371657,0.000007523871,0.00001701784,0.00001981958,0.00001598405],"domain_scores_gemma":[0.9999089,0.00001151681,0.00002410509,0.00001244684,0.00001310037,0.0000299451],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00006080055,0.000009523758,0.0002851365,0.00003248577,0.00000176873,0.00003653247,0.000005524385,0.00003915498,0.9974987,0.00004688031,0.00001813263,0.001965334],"study_design_scores_gemma":[0.00001783136,0.000296995,0.008818717,0.00001470479,0.00001373277,0.0004613623,0.00003361858,0.0003355277,0.9824064,0.00006114115,0.007533717,0.00000628736],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9884537,0.002487834,0.003390964,0.00004776878,0.00003511925,0.0000798794,0.001064697,0.00009279421,0.004347302],"genre_scores_gemma":[0.9899536,0.0008607068,0.004547826,0.00003677023,0.000006119717,0.00002665104,0.002307648,0.00002019712,0.002240608],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0006823764,"threshold_uncertainty_score":0.002013803,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03240120089313112,"score_gpt":0.233390337274655,"score_spread":0.2009891363815239,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}