{"id":"W2092713379","doi":"10.1111/j.1365-2958.2009.06854.x","title":"An outer membrane protease of the omptin family prevents activation of the <i>Citrobacter rodentium</i> PhoPQ two‐component system by antimicrobial peptides","year":2009,"lang":"en","type":"article","venue":"Molecular Microbiology","topic":"Antimicrobial Peptides and Activities","field":"Immunology and Microbiology","cited_by":29,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Montréal; McGill University","funders":"Canadian Institutes of Health Research; University of Washington","keywords":"Citrobacter rodentium; Biology; Protease; Microbiology; Citrobacter; Component (thermodynamics); Antimicrobial; Bacterial outer membrane; Antimicrobial peptides; Enterobacteriaceae; Biochemistry; Escherichia coli; Enzyme; Pathogen","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0002700724,0.0003893093,0.0006181615,0.00008543047,0.0002324255,0.00002119752,0.0009254028,0.0003524666,0.00002654352],"category_scores_gemma":[0.00002049598,0.0002537321,0.0004291922,0.0001971959,0.0005945191,0.0001371064,0.0002111448,0.000416127,0.00001858417],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00007219639,"about_ca_system_score_gemma":0.00008005615,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000238261,"about_ca_topic_score_gemma":0.000006182438,"domain_scores_codex":[0.9973041,0.0009182862,0.0007052445,0.0005115008,0.00005317073,0.000507644],"domain_scores_gemma":[0.9982648,0.00003946308,0.0006918882,0.0008494979,0.0001283145,0.00002607442],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002306057,0.0004469309,0.0003916097,0.00008122942,0.0001757832,0.000001834918,0.0001853615,0.0001184021,0.9955935,0.0001963004,0.002266974,0.0003114076],"study_design_scores_gemma":[0.001476877,0.000173353,0.00155158,0.0002689017,0.0001093477,0.0000873929,0.0001037551,0.000005023579,0.9940746,0.00001849147,0.00186853,0.0002621763],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9965353,0.0002540372,0.0006107349,0.0003894014,0.0006075351,0.001032667,0.000350495,0.00004613065,0.0001736887],"genre_scores_gemma":[0.9980995,0.000009839561,0.0001702353,0.001053716,0.0000305024,0.00001407588,0.0002278205,0.00003141743,0.0003628919],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001564191,"threshold_uncertainty_score":0.9999915,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.004891450117740815,"score_gpt":0.2021638372538142,"score_spread":0.1972723871360734,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}