{"id":"W2092727330","doi":"10.1038/ja.2013.117","title":"Glycopeptide antibiotic biosynthesis","year":2013,"lang":"en","type":"review","venue":"The Journal of Antibiotics","topic":"Microbial Natural Products and Biosynthesis","field":"Medicine","cited_by":205,"is_retracted":false,"has_abstract":false,"ca_institutions":"McMaster University","funders":"Canadian Institutes of Health Research; Canada Research Chairs","keywords":"Teicoplanin; Glycopeptide; Antibiotics; Glycopeptide antibiotic; Vancomycin; Microbiology; Bacteria; Antibiotic resistance; Biosynthesis; Antimicrobial; Biology; Nonribosomal peptide; Bacterial cell structure; Biochemistry; Enzyme; Staphylococcus aureus","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001173009,0.0005236335,0.002694539,0.0003577228,0.0001196509,0.00006837789,0.0006720694,0.0004248375,0.0002663896],"category_scores_gemma":[0.0006768745,0.0002270511,0.00108612,0.000526735,0.0002502787,0.0001005656,0.0001264436,0.001199273,0.0004267932],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001172456,"about_ca_system_score_gemma":0.000474001,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001288862,"about_ca_topic_score_gemma":8.632562e-7,"domain_scores_codex":[0.9972359,0.0003121402,0.0013983,0.000204938,0.0004570257,0.0003917176],"domain_scores_gemma":[0.996452,0.0005210645,0.00171163,0.0006947242,0.0004203563,0.000200175],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0000471813,0.0001654034,0.000002754368,0.01183699,0.0009746398,0.0000988366,0.00002606289,1.669361e-7,0.001790826,0.00001733469,0.02540254,0.9596373],"study_design_scores_gemma":[0.0001692474,0.000353253,0.00000570266,0.02825882,0.008340368,0.005400071,0.00003376527,0.000001156202,0.01095174,0.000006615051,0.9462033,0.0002759548],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0004600782,0.9968497,0.000006429448,0.0007628027,0.0007079206,0.000686995,0.00001970273,0.00001754147,0.0004888249],"genre_scores_gemma":[0.002196042,0.993103,0.001324958,0.0001818036,0.001411652,1.110687e-9,0.000005522931,0.00008645056,0.00169055],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9593613,"threshold_uncertainty_score":0.9258876,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05064687734870848,"score_gpt":0.3166767913961705,"score_spread":0.266029914047462,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}