{"id":"W2092804642","doi":"10.1021/bm700697a","title":"Polyamine Analogues Bind Human Serum Albumin","year":2007,"lang":"fi","type":"article","venue":"Biomacromolecules","topic":"Hemoglobin structure and function","field":"Biochemistry, Genetics and Molecular Biology","cited_by":188,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université du Québec à Trois-Rivières","funders":"National Cancer Institute; Natural Sciences and Engineering Research Council of Canada","keywords":"Polyamine; Chemistry; Human serum albumin; Spermine; Serum albumin; Protein secondary structure; Biochemistry; Binding constant; Nucleic acid; Albumin; Bovine serum albumin; Stereochemistry; Biophysics; Binding site; Enzyme; Biology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009572203,0.0002743974,0.0001904798,0.00009535407,0.0000929058,0.0001898521,0.0001845185,0.0003574295,0.001303031],"category_scores_gemma":[0.0002072769,0.00009377737,0.000209016,0.00009326013,0.0001082705,0.0001528422,0.0001930863,0.0002439033,0.0004853943],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000157865,"about_ca_system_score_gemma":0.00006319104,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005069977,"about_ca_topic_score_gemma":0.000451148,"domain_scores_codex":[0.9997992,0.00004839353,0.00001227243,0.00005847336,0.00005275977,0.00002891667],"domain_scores_gemma":[0.9998645,0.00004017479,0.0000343551,0.00001181271,0.0000297134,0.00001950501],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00004854672,0.000006708759,0.0002342157,0.00004001357,0.000007606218,0.00001779506,0.000008716747,0.00004358174,0.9983919,0.0000157533,0.00001589202,0.001169181],"study_design_scores_gemma":[0.000005071834,0.0003503168,0.003909939,0.000005830679,0.00001153525,0.0001388612,0.00001536414,0.0005934505,0.9926578,0.00001785923,0.002290313,0.000003662422],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9895889,0.00338263,0.005007952,0.00005401131,0.00002000701,0.00003474419,0.0001015884,0.00004488837,0.001765238],"genre_scores_gemma":[0.9917088,0.000958588,0.003470303,0.0001215941,0.00001307064,0.00002710581,0.0003239063,0.00001733435,0.003359271],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001303031,"threshold_uncertainty_score":0.004359007,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009364719517904047,"score_gpt":0.2714113668058549,"score_spread":0.2620466472879508,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}