{"id":"W2092855364","doi":"10.1016/s0009-9236(03)90700-4","title":"CYP3A and P‐glycoprotein induction with St. John's wort in healthy volunteers of selected ethnic populations","year":2003,"lang":"en","type":"article","venue":"Clinical Pharmacology & Therapeutics","topic":"Phytochemistry and biological activity of medicinal plants","field":"Agricultural and Biological Sciences","cited_by":4,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"","keywords":"CYP3A; Ethnic group; Traditional medicine; Glycoprotein; Medicine; Pharmacology; Internal medicine; Biology; Anthropology; Genetics; Sociology; Metabolism; Cytochrome P450","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005472071,0.000133861,0.0003168963,0.00001353907,0.00007983937,0.000004268999,0.0001130667,0.0002587973,0.0001593064],"category_scores_gemma":[0.00005170629,0.00005453157,0.00004117494,0.0004296032,0.0003421765,0.00005533336,0.00001983597,0.0005264074,0.000002146998],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001932925,"about_ca_system_score_gemma":0.00002967756,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0000391628,"about_ca_topic_score_gemma":0.0002247215,"domain_scores_codex":[0.9985607,0.0003798456,0.0003843602,0.0003010591,0.0001161691,0.0002578661],"domain_scores_gemma":[0.9991645,0.0004566615,0.000152202,0.00003804833,0.00007391004,0.0001146432],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.002831753,0.001734116,0.2698544,0.00002908394,0.0001517831,0.00001759577,0.00006449185,0.00001755525,0.6635494,0.00002688739,0.0004927213,0.06123024],"study_design_scores_gemma":[0.001450252,0.003328118,0.9782205,0.00003441787,0.0001082368,0.0000320023,0.0001610597,0.00007805569,0.009504023,0.0005022923,0.006358713,0.0002222808],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9953671,0.0003471928,0.000006778173,0.003690894,0.000172546,0.000286065,0.00001592754,0.00002493981,0.00008863318],"genre_scores_gemma":[0.995241,0.000519256,0.000146531,0.00389188,0.0001324647,0.00001360819,0.00002823896,0.000001024935,0.00002601061],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.7083662,"threshold_uncertainty_score":0.2287008,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1502681105744469,"score_gpt":0.3859513797236898,"score_spread":0.235683269149243,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}