{"id":"W2092873084","doi":"10.1016/s1471-4892(01)00080-7","title":"Pharmacokinetics and pharmacodynamics of the new fluoroquinolones: focus on respiratory infections","year":2001,"lang":"en","type":"review","venue":"Current Opinion in Pharmacology","topic":"Antibiotics Pharmacokinetics and Efficacy","field":"Medicine","cited_by":94,"is_retracted":false,"has_abstract":false,"ca_institutions":"Manitoba Health; Health Sciences Centre; University of Manitoba","funders":"","keywords":"Moxifloxacin; Levofloxacin; Pharmacodynamics; Gatifloxacin; Moraxella catarrhalis; Gemifloxacin; Medicine; Streptococcus pneumoniae; Pharmacology; Pharmacokinetics; Respiratory tract infections; Antibiotics; Respiratory system; Microbiology; Biology; Internal medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0002960211,0.00066771,0.00170045,0.000749666,0.00009852739,0.00001527921,0.0004138006,0.0003713351,0.0002629522],"category_scores_gemma":[0.00006166963,0.0005016776,0.0005124073,0.001221993,0.0003675966,0.00004250326,0.0003515177,0.001913518,0.00003315312],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000221586,"about_ca_system_score_gemma":0.0007908914,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000008342177,"about_ca_topic_score_gemma":7.926265e-7,"domain_scores_codex":[0.9967161,0.0004033657,0.001281939,0.0006945487,0.0003513004,0.0005527089],"domain_scores_gemma":[0.9980823,0.0003688899,0.0006905409,0.0004179614,0.0001118854,0.0003284468],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00008346909,0.001164205,0.0002506969,0.01306675,0.0003021655,0.000008182752,0.00005459985,0.00003944931,0.0001107447,0.0003365645,0.0506952,0.933888],"study_design_scores_gemma":[0.00357969,0.0003363506,0.0001305074,0.008279681,0.001718648,0.00009902316,0.000003935288,0.0002611557,0.000118387,0.00005084703,0.9850355,0.000386228],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0002902512,0.9804085,0.0000530937,0.0004603761,0.01603212,0.002192602,0.00008776448,0.00005223068,0.000423105],"genre_scores_gemma":[0.0005396905,0.9967977,0.00001961807,0.0001740424,0.00214696,0.0000529077,0.00005376186,0.00009946938,0.000115819],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9343404,"threshold_uncertainty_score":0.9997435,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1114151534871354,"score_gpt":0.4472112334260294,"score_spread":0.3357960799388939,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}