{"id":"W2092894652","doi":"10.1007/s10719-011-9332-7","title":"Investigating the potential of conserved inner core oligosaccharide regions of Moraxella catarrhalis lipopolysaccharide as vaccine antigens: accessibility and functional activity of monoclonal antibodies and glycoconjugate derived sera","year":2011,"lang":"en","type":"article","venue":"Glycoconjugate Journal","topic":"Pneumonia and Respiratory Infections","field":"Medicine","cited_by":21,"is_retracted":false,"has_abstract":false,"ca_institutions":"Institute for Biological Sciences","funders":"University at Buffalo; Ireland Canada University Foundation","keywords":"Moraxella catarrhalis; Monoclonal antibody; Epitope; Glycoconjugate; Mutant; Microbiology; Biology; Antigen; Lipopolysaccharide; Lipid A; Serotype; Antibody; Virology; Haemophilus influenzae; Immunology; Biochemistry; Gene; Antibiotics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005840859,0.0003687988,0.0001460063,0.0002294859,0.0001272335,0.0002427614,0.0002676104,0.0004045102,0.0007578073],"category_scores_gemma":[0.0004456851,0.0001385704,0.0002749515,0.00009405635,0.0002180287,0.0002744366,0.0001796114,0.0003566395,0.0001665386],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002269847,"about_ca_system_score_gemma":0.0001201863,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005457451,"about_ca_topic_score_gemma":0.0003855152,"domain_scores_codex":[0.9998444,0.00006390008,0.000007821041,0.00001701064,0.00002174619,0.00004510357],"domain_scores_gemma":[0.999788,0.0001148339,0.00001618828,0.00002266399,0.00003706846,0.00002128375],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003047892,0.00006036072,0.0004248825,0.0000368387,0.000006255072,0.00002776295,0.00002252171,0.00009968376,0.9968767,0.00009167993,0.00001013177,0.002038281],"study_design_scores_gemma":[0.00003429859,0.001255983,0.003431367,0.00000547514,0.00003105921,0.0001786765,0.00003278127,0.001040953,0.9930519,0.00006968259,0.0008654293,0.000002426453],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9965615,0.0008001408,0.001779244,0.00004829849,0.00001198335,0.00001428752,0.00002495643,0.000009557617,0.0007500501],"genre_scores_gemma":[0.9982489,0.0004108968,0.0007067457,0.00003683155,0.000009053372,0.000009391565,0.00008420491,0.000004751395,0.0004892054],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0007578073,"threshold_uncertainty_score":0.003088951,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05226165906720615,"score_gpt":0.2827700060364365,"score_spread":0.2305083469692304,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}