{"id":"W2092896180","doi":"10.1038/nsmb1053","title":"Sequence-specific recognition of RNA hairpins by the SAM domain of Vts1p","year":2006,"lang":"en","type":"article","venue":"Nature Structural & Molecular Biology","topic":"RNA Research and Splicing","field":"Biochemistry, Genetics and Molecular Biology","cited_by":118,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Toronto; Lunenfeld-Tanenbaum Research Institute; Mount Sinai Hospital","funders":"Francis Crick Institute","keywords":"RNA; Biology; Saccharomyces cerevisiae; RNA-binding protein; Computational biology; Base pair; Riboswitch; Cell biology; Genetics; Non-coding RNA; Yeast; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001777106,0.0001828706,0.0002251481,0.000056692,0.00007557044,0.000009282568,0.0003666409,0.0004993172,0.00003277807],"category_scores_gemma":[0.00006928923,0.0001245474,0.0001634493,0.000171025,0.0004021049,0.000003726415,0.00009827327,0.0003563896,0.000001631788],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001643347,"about_ca_system_score_gemma":0.00005003306,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001324282,"about_ca_topic_score_gemma":0.0000424485,"domain_scores_codex":[0.9986635,0.0001933609,0.0003089686,0.0003462986,0.0001624524,0.0003254054],"domain_scores_gemma":[0.9991786,0.00001978031,0.0001803249,0.0003820071,0.0001927429,0.00004651163],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001060009,0.000009977491,0.0003706888,0.00001269808,0.00004431451,0.00000338528,0.000005149764,0.000009627844,0.9896277,0.002141456,0.002374775,0.005294221],"study_design_scores_gemma":[0.0004659052,0.0003067272,0.001422341,0.00001088377,0.000009125311,0.00003642771,0.00002496866,0.00001350388,0.9837702,0.007202592,0.006588782,0.0001485738],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9915076,0.005463078,0.001174827,0.0004523769,0.0001408941,0.0002353769,0.0003156005,0.000007359012,0.0007028843],"genre_scores_gemma":[0.9970112,0.0001124482,0.00118683,0.0002007593,0.0001320488,0.000009229108,0.001199822,0.00001713617,0.0001304881],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.005857537,"threshold_uncertainty_score":0.5078894,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007978099519191878,"score_gpt":0.2892903177934182,"score_spread":0.2813122182742264,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}