{"id":"W2092918019","doi":"10.1016/j.jaut.2009.06.005","title":"Congenital heart block: Identification of autoantibody binding site on the extracellular loop (domain I, S5–S6) of α1D L-type Ca channel","year":2009,"lang":"en","type":"article","venue":"Journal of Autoimmunity","topic":"Viral Infections and Immunology Research","field":"Medicine","cited_by":65,"is_retracted":false,"has_abstract":false,"ca_institutions":"Université Laval","funders":"National Heart, Lung, and Blood Institute; National Institutes of Health","keywords":"Autoantibody; Extracellular; Medicine; Ribonucleoprotein; Antibody; Immunology; Internal medicine; Biology; Biochemistry; RNA","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002132582,0.0001253131,0.0004338529,0.0004051889,0.0002154089,0.00001994911,0.0001992611,0.0001283598,0.0001142464],"category_scores_gemma":[0.0004614814,0.00008576368,0.0002243851,0.0005245444,0.0002359671,0.0001838143,0.00003750283,0.000908024,0.00003828924],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00007361353,"about_ca_system_score_gemma":0.000199638,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00005256176,"about_ca_topic_score_gemma":0.000001209385,"domain_scores_codex":[0.9981877,0.0003071141,0.0008184069,0.00008927972,0.0003877693,0.0002097103],"domain_scores_gemma":[0.9980546,0.0001643785,0.0005945342,0.000420456,0.0007103116,0.00005571638],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.0004548386,0.0007483769,0.002876644,0.00002515032,0.000204459,0.00001957722,0.0003364624,0.0000703861,0.9940354,0.0001578868,0.0005755945,0.0004951965],"study_design_scores_gemma":[0.002451769,0.007377706,0.6741302,0.0005333498,0.0002813677,0.001038704,0.001605889,0.001266492,0.3080095,0.0003554303,0.002748772,0.0002007817],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9950699,0.001621356,0.00005479173,0.002454609,0.0002522867,0.0002178932,0.00001322915,0.000009292534,0.0003065965],"genre_scores_gemma":[0.998728,0.0002643719,0.00005989897,0.00005911959,0.00005460431,7.14867e-7,0.00001025003,0.00001048646,0.0008124891],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.6860259,"threshold_uncertainty_score":0.3944963,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03431851331474464,"score_gpt":0.3216103072674007,"score_spread":0.287291793952656,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}