{"id":"W2092918019","doi":"10.1016/j.jaut.2009.06.005","title":"Congenital heart block: Identification of autoantibody binding site on the extracellular loop (domain I, S5–S6) of α1D L-type Ca channel","year":2009,"lang":"en","type":"article","venue":"Journal of Autoimmunity","topic":"Viral Infections and Immunology Research","field":"Medicine","cited_by":65,"is_retracted":false,"has_abstract":false,"ca_institutions":"Université Laval","funders":"National Heart, Lung, and Blood Institute; National Institutes of Health","keywords":"Autoantibody; Extracellular; Medicine; Ribonucleoprotein; Antibody; Immunology; Internal medicine; Biology; Biochemistry; RNA","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001120432,0.0003154595,0.000340062,0.0002242149,0.0002337279,0.0001639505,0.0003340085,0.0008614279,0.002472517],"category_scores_gemma":[0.000409216,0.0001295729,0.0004885517,0.0001226051,0.0002985804,0.0001663943,0.0002059359,0.0004274295,0.0005562407],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002125722,"about_ca_system_score_gemma":0.0001266865,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009904886,"about_ca_topic_score_gemma":0.0006358832,"domain_scores_codex":[0.9998704,0.00002082384,0.00001343001,0.00003598091,0.00002922503,0.00003011669],"domain_scores_gemma":[0.9996746,0.0001045325,0.0000862472,0.00002300117,0.00002753836,0.00008410094],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001111075,0.0001386978,0.009550456,0.00008970369,0.00004088224,0.01046867,0.0001671842,0.0004221717,0.9737802,0.0003810974,0.00029049,0.003559418],"study_design_scores_gemma":[0.0002785591,0.001947244,0.1360455,0.00006251816,0.0001550209,0.05140786,0.0002874325,0.00760431,0.7986539,0.0006102344,0.002895599,0.00005185295],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.997829,0.0001910082,0.001006257,0.00009717866,0.00002489724,0.000009311211,0.0001141673,0.00001312236,0.0007151235],"genre_scores_gemma":[0.9991034,0.00004582632,0.000378711,0.00006262426,0.000009664537,0.000002243247,0.000125767,0.00000356785,0.0002682627],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002472517,"threshold_uncertainty_score":0.008271396,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03431851331474464,"score_gpt":0.3216103072674007,"score_spread":0.287291793952656,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}