{"id":"W2092972513","doi":"10.1111/j.1600-065x.2009.00765.x","title":"Immune regulation by 4‐1BB and 4‐1BBL: complexities and challenges","year":2009,"lang":"en","type":"review","venue":"Immunological Reviews","topic":"Immune Response and Inflammation","field":"Immunology and Microbiology","cited_by":301,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"","keywords":"Immune system; Biology; Immune receptor; Immunology; CD8; Receptor; T cell; Immunotherapy; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0008296252,0.0007464678,0.0013404,0.0008805991,0.0002971211,0.0009176989,0.0008403427,0.00128484,0.001605354],"category_scores_gemma":[0.0004868435,0.0002372439,0.0002610056,0.001064386,0.0007131318,0.001902743,0.0005902903,0.001948439,0.001723771],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0009012882,"about_ca_system_score_gemma":0.001115611,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008314466,"about_ca_topic_score_gemma":0.001404351,"domain_scores_codex":[0.9998143,0.0000413646,0.00002284355,0.00003034234,0.00007026987,0.00002082885],"domain_scores_gemma":[0.9997857,0.00007351091,0.00002446409,0.000007847717,0.00007955061,0.0000290281],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001308735,0.00006714942,0.0002052316,0.007531299,0.0000461874,0.0003857113,0.0001379659,0.0007161348,0.01387159,0.01404606,0.02963853,0.9332232],"study_design_scores_gemma":[0.00001862041,0.00008950048,0.0006866469,0.001363054,0.00003087198,0.001389927,0.0001600427,0.0001699853,0.001718816,0.006848811,0.9875004,0.00002324214],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0002105753,0.9978981,0.0002383688,0.0006474702,0.000380722,0.00000153149,0.00000423295,0.000005169317,0.000613845],"genre_scores_gemma":[0.001205894,0.9964345,0.000343459,0.0004216234,0.0004696843,0.000005639195,0.00001217811,0.000001993301,0.001105171],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.001605354,"threshold_uncertainty_score":0.006539285,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1267117739713093,"score_gpt":0.3245160031348436,"score_spread":0.1978042291635343,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}