{"id":"W2092977812","doi":"10.3109/14653241003628167","title":"Clonogenic assays measure leukemia stem cell killing not detectable by chromium release and flow cytometric cytotoxicity assays","year":2010,"lang":"en","type":"article","venue":"Cytotherapy","topic":"Immune Cell Function and Interaction","field":"Immunology and Microbiology","cited_by":17,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Toronto; Princess Margaret Cancer Centre","funders":"National Cancer Institute; University Health Network","keywords":"Clonogenic assay; Cytotoxicity; Flow cytometry; Biology; Stem cell; Population; Molecular biology; Cell culture; Chemistry; Cell; Immunology; Cancer research; Cell biology; In vitro; Biochemistry; Medicine","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":["insufficient_payload"],"category_scores_codex":[0.0005941791,0.0003710801,0.0004284182,0.0003192493,0.0004795339,0.00008227357,0.0002555114,0.0006750257,0.002148911],"category_scores_gemma":[0.00004708575,0.0003478669,0.0001742653,0.000408651,0.0001528293,0.0002743015,0.00004582387,0.001212229,0.0007825982],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001987829,"about_ca_system_score_gemma":0.000125892,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001312499,"about_ca_topic_score_gemma":0.00002361063,"domain_scores_codex":[0.9980843,0.0002439851,0.0004386017,0.0005815095,0.00009500066,0.0005565913],"domain_scores_gemma":[0.9988099,0.0002324394,0.0002337309,0.0004989328,0.0001471767,0.00007781426],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0004901491,0.0001083326,0.0004970863,0.00001768314,0.0001090598,0.000002510613,0.0001794823,0.00001254183,0.9746197,0.00001385033,0.01387163,0.01007798],"study_design_scores_gemma":[0.00241642,0.0002819395,0.0006065694,0.00001418855,0.00003716333,0.00009296657,0.0001095425,0.0004217169,0.8979951,0.000008042947,0.09764249,0.0003738922],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9841272,0.003996917,0.00492823,0.0001146416,0.003846826,0.0003968698,0.00003247636,0.0002358455,0.002321002],"genre_scores_gemma":[0.9816127,0.0007249784,0.0002296348,0.0006852251,0.0001198713,0.00004344008,0.00008135854,0.00006872026,0.01643405],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.08377086,"threshold_uncertainty_score":0.9999954,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009195141372960926,"score_gpt":0.2096870477747034,"score_spread":0.2004919064017425,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}