{"id":"W2092998218","doi":"10.1016/j.vaccine.2005.07.032","title":"Highly conserved pattern of recognition of influenza A wild-type and variant CD8+ CTL epitopes in HLA-A2+ humans and transgenic HLA-A2+/H2 class I-deficient mice","year":2005,"lang":"en","type":"article","venue":"Vaccine","topic":"T-cell and B-cell Immunology","field":"Immunology and Microbiology","cited_by":14,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Toronto; Hospital for Sick Children","funders":"Ontario HIV Treatment Network","keywords":"Epitope; CTL*; Biology; Human leukocyte antigen; CD8; Virology; Immunology; Cytotoxic T cell; Major histocompatibility complex; T-cell receptor; MHC class I; Antigen; Molecular biology; T cell; Immune system; Genetics; In vitro","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00008065061,0.000276531,0.0002206507,0.0002694293,0.000110401,0.0001902231,0.0001881193,0.0003912698,0.001540927],"category_scores_gemma":[0.00012963,0.0001465285,0.0001674982,0.00007607925,0.0001838168,0.0001427028,0.000100138,0.0004985934,0.0003432265],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000124363,"about_ca_system_score_gemma":0.00005966771,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000352403,"about_ca_topic_score_gemma":0.0001988427,"domain_scores_codex":[0.9999131,0.00001157638,0.000007209644,0.00002716652,0.00001063912,0.00003044407],"domain_scores_gemma":[0.9998841,0.00002567393,0.00002421624,0.00001572584,0.00001004051,0.00004019452],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0005290888,0.00002905476,0.0007333171,0.00001075115,0.00000829268,0.0001524719,0.00001594321,0.00002822938,0.9976994,0.00007785021,0.00004256935,0.0006728548],"study_design_scores_gemma":[0.000233707,0.002939951,0.1565297,0.00002020101,0.0001200522,0.009622627,0.0002084954,0.002363018,0.8246655,0.0005471618,0.002717176,0.00003252121],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9987782,0.0001930569,0.0003211654,0.00002626739,0.000008953273,0.00000365086,0.0001925722,0.00001325957,0.0004629671],"genre_scores_gemma":[0.9986885,0.0000727303,0.0001727228,0.00003446986,0.000006942717,0.000005115876,0.0002574174,0.000008027085,0.0007540821],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001540927,"threshold_uncertainty_score":0.005154908,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01933166826942119,"score_gpt":0.2325925366424419,"score_spread":0.2132608683730208,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}