{"id":"W2093015607","doi":"10.1161/01.cir.0000155252.23933.2d","title":"Sildenafil Prevents Endothelial Dysfunction Induced by Ischemia and Reperfusion via Opening of Adenosine Triphosphate–Sensitive Potassium Channels","year":2005,"lang":"en","type":"article","venue":"Circulation","topic":"Cardiac Ischemia and Reperfusion","field":"Medicine","cited_by":132,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Heart and Stroke Foundation of Canada","keywords":"Medicine; Sildenafil; Glibenclamide; Placebo; Ischemia; Vasodilation; Crossover study; Brachial artery; Anesthesia; Potassium channel opener; Endothelial dysfunction; Potassium channel; Endothelium; Internal medicine; Adenosine; Pharmacology; Cardiology; Endocrinology; Blood pressure; Diabetes mellitus; Pathology","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004438516,0.0005305553,0.0008766924,0.0001658227,0.0001670085,0.0003781006,0.0002475664,0.0004034958,0.001172528],"category_scores_gemma":[0.0004130288,0.0001884286,0.0003059626,0.0001387598,0.0002953815,0.0002220708,0.0001590838,0.0008937172,0.0002772744],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001272251,"about_ca_system_score_gemma":0.0001659565,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001501029,"about_ca_topic_score_gemma":0.000321253,"domain_scores_codex":[0.9998348,0.00004506771,0.0000172921,0.00002123683,0.00003467034,0.00004693967],"domain_scores_gemma":[0.9997051,0.00005892648,0.0001342227,0.00001710065,0.00001774204,0.00006687984],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.06920812,0.00944588,0.01268566,0.002062498,0.0005317882,0.0004917355,0.0001699851,0.0005350485,0.7668169,0.0002933904,0.001798151,0.1359609],"study_design_scores_gemma":[0.02890341,0.2769989,0.3995144,0.0004133711,0.002437744,0.002302024,0.0002491396,0.005617252,0.2723451,0.0003957293,0.01073467,0.00008840624],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.990538,0.007431904,0.0006165112,0.0001880815,0.0001537381,0.0000671794,0.00008638619,0.00007087451,0.0008472612],"genre_scores_gemma":[0.9917949,0.005118829,0.001026034,0.0003953721,0.000516462,0.00005709951,0.000295055,0.00001114472,0.0007851921],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001172528,"threshold_uncertainty_score":0.003922522,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01046296864363973,"score_gpt":0.2434723255702795,"score_spread":0.2330093569266397,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}