{"id":"W2093060998","doi":"10.1186/1745-6215-12-252","title":"Update on the third international stroke trial (IST-3) of thrombolysis for acute ischaemic stroke and baseline features of the 3035 patients recruited","year":2011,"lang":"en","type":"article","venue":"Trials","topic":"Acute Ischemic Stroke Management","field":"Medicine","cited_by":40,"is_retracted":false,"has_abstract":true,"ca_institutions":"Queen Elizabeth II Health Sciences Centre; Dalhousie University","funders":"Medical Research Council; Stockholms Läns Landsting; National Research Foundation; Karolinska Institutet; University of Glasgow; Schweizerische Herzstiftung; University of Oxford; Chest Heart and Stroke Scotland; University of Nottingham; National Health and Medical Research Council; Norges Forskningsråd; Dalhousie University; Scottish Funding Council; Novo Nordisk; National Institute for Health and Care Research; University of Edinburgh; Sanofi; Stroke Association; McMaster University; National Institute for Social Care and Health Research","keywords":"Medicine; Thrombolysis; Stroke (engine); Context (archaeology); Clinical trial; Randomized controlled trial; Ischaemic stroke; Fibrinolytic agent; Physical therapy; Tissue plasminogen activator; Surgery; Internal medicine; Ischemia; Myocardial infarction","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002131703,0.0001865751,0.0007540724,0.0001214488,0.00005304069,0.000009537627,0.0003645236,0.00009887557,0.0003474205],"category_scores_gemma":[0.002761559,0.00009447803,0.000360786,0.0001100965,0.0001422423,0.00004630578,0.00017546,0.0001672524,0.00000346848],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003464274,"about_ca_system_score_gemma":0.00004157814,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00003876105,"about_ca_topic_score_gemma":0.000004132276,"domain_scores_codex":[0.997932,0.0002562371,0.0008679248,0.0002591963,0.0005157393,0.0001688961],"domain_scores_gemma":[0.9974765,0.0008542815,0.0008516168,0.0005367176,0.0002361629,0.00004478494],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.2316226,0.001800237,0.008405926,0.0001690375,0.01307732,0.000004020563,0.002390147,0.000003049282,0.0934788,0.00436263,0.6205491,0.02413717],"study_design_scores_gemma":[0.1925367,0.004030115,0.03419516,0.0004990224,0.009552837,0.000005960444,0.0009536253,0.0001848184,0.711485,0.0004979908,0.04558756,0.0004711698],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9800115,0.00008092209,0.0002900682,0.002865056,0.001199206,0.004692995,0.001546686,0.00002238922,0.009291188],"genre_scores_gemma":[0.9920029,0.000161811,0.001592923,0.0008894256,0.000430232,0.000191982,0.0001269064,0.00002742653,0.004576372],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.6180062,"threshold_uncertainty_score":0.3852702,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0959570186215833,"score_gpt":0.3521614051842738,"score_spread":0.2562043865626905,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}