{"id":"W2093119618","doi":"10.1016/j.phrs.2011.11.004","title":"Prolonged signalling and trafficking of the bradykinin B2 receptor stimulated with the amphibian peptide maximakinin: Insight into the endosomal inactivation of kinins","year":2011,"lang":"en","type":"article","venue":"Pharmacological Research","topic":"Coagulation, Bradykinin, Polyphosphates, and Angioedema","field":"Medicine","cited_by":19,"is_retracted":false,"has_abstract":false,"ca_institutions":"Université Laval; Centre hospitalier universitaire de Québec","funders":"Canadian Institutes of Health Research","keywords":"Bradykinin; Kinin; Chemistry; Agonist; Receptor; Peptide; Bradykinin receptor; Molecular biology; Cell biology; Biochemistry; Biology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001698568,0.0001872664,0.000332825,0.0001256191,0.0004469535,0.00002499882,0.0003938804,0.0001214563,0.0003411376],"category_scores_gemma":[0.0005484113,0.00007997129,0.0001000314,0.0009226261,0.001241137,0.000119087,0.0002074287,0.0007633895,0.00000308962],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00006364219,"about_ca_system_score_gemma":0.0002157739,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000189823,"about_ca_topic_score_gemma":0.00005968202,"domain_scores_codex":[0.9972275,0.000706778,0.0004186328,0.0003405417,0.0008930233,0.0004135254],"domain_scores_gemma":[0.9974479,0.001460011,0.0002318409,0.0002596921,0.0004793458,0.000121219],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.008050397,0.001140758,0.1435585,0.0002016515,0.0005883118,0.00003601632,0.04321358,0.0001877111,0.7641237,0.002082438,0.000842013,0.03597485],"study_design_scores_gemma":[0.003475785,0.002045049,0.4890555,0.0002817919,0.0002181786,0.00002445585,0.00211542,0.004256896,0.4961556,0.0003020196,0.001874645,0.0001946371],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9927059,0.0004816002,0.00004253049,0.00370257,0.00005486489,0.001333939,0.000003399313,0.00003429342,0.001640838],"genre_scores_gemma":[0.9989669,0.0001089206,0.0002291433,0.0002516862,0.0001240566,0.00008403924,0.000005286623,0.00002339675,0.0002066271],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.345497,"threshold_uncertainty_score":0.4573021,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1324282358993413,"score_gpt":0.3588751937291391,"score_spread":0.2264469578297978,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}