{"id":"W2093224358","doi":"10.1074/jbc.m313678200","title":"Involvement of Glycosylphosphatidylinositol-linked Ceruloplasmin in the Copper/Zinc-Nitric Oxide-dependent Degradation of Glypican-1 Heparan Sulfate in Rat C6 Glioma Cells","year":2004,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Proteoglycans and glycosaminoglycans research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":30,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University; Montreal General Hospital","funders":"Lunds Universitet; Universiteit van Amsterdam","keywords":"Ceruloplasmin; Heparan sulfate; Nitric oxide; Chemistry; Copper; Zinc; Degradation (telecommunications); Glioma; Biochemistry; Cell biology; Biophysics; Glycosaminoglycan; Cancer research; Biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001105596,0.0003470024,0.000232776,0.0001223231,0.0001301642,0.0002260584,0.0001263191,0.000186701,0.0002919738],"category_scores_gemma":[0.00007295355,0.0001074798,0.0002462098,0.0001036888,0.0001762094,0.0001298549,0.0001505948,0.0002632258,0.0001556083],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002567246,"about_ca_system_score_gemma":0.0002350112,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001798163,"about_ca_topic_score_gemma":0.0017026,"domain_scores_codex":[0.9998977,0.00001734419,0.00001185224,0.00002114708,0.00003064032,0.00002137449],"domain_scores_gemma":[0.9999311,0.000005871357,0.00002184015,0.000009351145,0.00001252414,0.00001937909],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00005864277,0.000005833801,0.0001171984,0.00002142509,0.000003001624,0.00005370807,0.00001532924,0.00001851759,0.9993671,0.00002593037,0.000006009906,0.0003074406],"study_design_scores_gemma":[0.00000649253,0.00008213572,0.007499369,0.000003021277,0.00001242588,0.0002359366,0.00003542569,0.000630538,0.9907508,0.00002308157,0.0007168532,0.000003886596],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9965242,0.001369791,0.001207117,0.000042578,0.000008933016,0.00001202063,0.0002127769,0.00002880205,0.0005938977],"genre_scores_gemma":[0.9960541,0.0006006982,0.001460745,0.00002817471,0.000002969111,0.00002002737,0.0002926873,0.000007447058,0.001533104],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001798163,"threshold_uncertainty_score":0.003575385,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02253735299037408,"score_gpt":0.2706638754399909,"score_spread":0.2481265224496168,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}