{"id":"W2093225553","doi":"10.1016/j.jsbmb.2007.03.036","title":"Steroid metabolism and profile of steroidogenic gene expression in Episkin™: High similarity with human epidermis","year":2007,"lang":"en","type":"article","venue":"The Journal of Steroid Biochemistry and Molecular Biology","topic":"Hormonal and reproductive studies","field":"Medicine","cited_by":23,"is_retracted":false,"has_abstract":false,"ca_institutions":"Wilfrid Laurier University; Université Laval","funders":"F. Hoffmann-La Roche","keywords":"Dehydroepiandrosterone; Androstenedione; Hydroxysteroid; Dihydrotestosterone; Steroid; Pregnenolone; Androstenediol; Internal medicine; Endocrinology; Metabolism; Estrone; Sulfotransferase; Hydroxysteroid dehydrogenase; Chemistry; Dehydrogenase; Androsterone; Biology; Androgen; Dehydroepiandrosterone sulfate; Enzyme; Biochemistry; Estrogen; Hormone","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0000679928,0.0001204304,0.000219626,0.0004336629,0.0001719631,0.0003531422,0.00008449243,0.0001062291,0.002155899],"category_scores_gemma":[0.0001386612,0.00007477147,0.0001896934,0.0003433471,0.0001355048,0.00007217543,0.0001331536,0.0002023058,0.0006525646],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0000887142,"about_ca_system_score_gemma":0.0001160305,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006613794,"about_ca_topic_score_gemma":0.0003138674,"domain_scores_codex":[0.9999442,0.000006029048,0.000004701225,0.00001441933,0.0000133623,0.00001729676],"domain_scores_gemma":[0.9999441,0.00001156541,0.000007984197,0.000009116752,0.0000111588,0.000015986],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001017712,0.00006575394,0.01366324,0.00005049594,0.00003139928,0.0006068856,0.0002147473,0.00005004038,0.9758277,0.0001806127,0.00007827187,0.008213056],"study_design_scores_gemma":[0.00004228542,0.001193678,0.6046714,0.00002380273,0.0002266517,0.009658584,0.001054581,0.0004762099,0.3681769,0.0003989346,0.01405073,0.00002625827],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9955515,0.00109334,0.0007161232,0.00001733622,0.00001393186,0.00001903914,0.0003840255,0.00001545154,0.002189214],"genre_scores_gemma":[0.9958529,0.0008251384,0.0004178618,0.00001546667,0.00001017614,0.00001524626,0.0007759449,0.000006026104,0.002081186],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002155899,"threshold_uncertainty_score":0.007212222,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01023631718219471,"score_gpt":0.2739075860600617,"score_spread":0.263671268877867,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}