{"id":"W2093225553","doi":"10.1016/j.jsbmb.2007.03.036","title":"Steroid metabolism and profile of steroidogenic gene expression in Episkin™: High similarity with human epidermis","year":2007,"lang":"en","type":"article","venue":"The Journal of Steroid Biochemistry and Molecular Biology","topic":"Hormonal and reproductive studies","field":"Medicine","cited_by":23,"is_retracted":false,"has_abstract":false,"ca_institutions":"Wilfrid Laurier University; Université Laval","funders":"F. Hoffmann-La Roche","keywords":"Dehydroepiandrosterone; Androstenedione; Hydroxysteroid; Dihydrotestosterone; Steroid; Pregnenolone; Androstenediol; Internal medicine; Endocrinology; Metabolism; Estrone; Sulfotransferase; Hydroxysteroid dehydrogenase; Chemistry; Dehydrogenase; Androsterone; Biology; Androgen; Dehydroepiandrosterone sulfate; Enzyme; Biochemistry; Estrogen; Hormone","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0008376682,0.0001551002,0.0004744524,0.00006660901,0.00006236073,0.000003059392,0.00008750878,0.000106009,0.000004668135],"category_scores_gemma":[0.00005584084,0.00008131272,0.00005035096,0.00008131571,0.00035808,0.00002460537,0.0001026742,0.0002605444,9.820268e-8],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001275209,"about_ca_system_score_gemma":0.00002759213,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001232466,"about_ca_topic_score_gemma":0.000003406569,"domain_scores_codex":[0.9989838,0.00009449561,0.0004310422,0.0001797457,0.0001236568,0.0001872802],"domain_scores_gemma":[0.9992138,0.00005154937,0.0003158587,0.0001809482,0.0001532872,0.00008454403],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001199807,0.00009314151,0.00668152,0.00009282648,0.0001412914,0.00005724547,0.0002487643,8.597881e-7,0.9907201,0.000009170083,0.000007124002,0.0007481468],"study_design_scores_gemma":[0.001635041,0.0006135054,0.05865152,0.00009767036,0.0001232679,0.0006546835,0.0004298038,5.289685e-7,0.9374639,0.0002151702,0.00003187512,0.00008299868],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9864455,0.01211767,0.0007242652,0.000468428,0.0000264344,0.0001406123,0.000008167236,0.000002529866,0.00006634796],"genre_scores_gemma":[0.9982058,0.0005464062,0.0009975322,0.00009522036,0.0001028272,0.000001328905,0.000005238177,0.000008665776,0.00003692808],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.05325617,"threshold_uncertainty_score":0.3315836,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01023631718219471,"score_gpt":0.2739075860600617,"score_spread":0.263671268877867,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}