{"id":"W2093264625","doi":"10.1126/science.301.5630.168","title":"Toxicity and Protection in Prions","year":2003,"lang":"en","type":"letter","venue":"Science","topic":"Prion Diseases and Protein Misfolding","field":"Biochemistry, Genetics and Molecular Biology","cited_by":5,"is_retracted":false,"has_abstract":true,"ca_institutions":"Jewish General Hospital","funders":"","keywords":"Toxicity; Biology; Toxicology; Chemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002763694,0.00068587,0.001090999,0.0005060121,0.001272226,0.00181203,0.001316213,0.01535429,0.003046226],"category_scores_gemma":[0.006323754,0.0003216655,0.0005857797,0.0002333531,0.003947231,0.003241102,0.001490631,0.009843547,0.002628531],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00224707,"about_ca_system_score_gemma":0.0007106629,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005504225,"about_ca_topic_score_gemma":0.0008078002,"domain_scores_codex":[0.9985846,0.0004341543,0.0001202695,0.0002161153,0.0004786248,0.0001662335],"domain_scores_gemma":[0.9975989,0.001297061,0.0001933344,0.0001864414,0.0003928631,0.0003312397],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.001310321,0.0001625073,0.0008296581,0.0008722328,0.00008870011,0.006595997,0.000336558,0.0004507941,0.02158871,0.09782055,0.7744868,0.09545729],"study_design_scores_gemma":[0.0004079627,0.0005978817,0.001761413,0.0004650088,0.00004152283,0.007928435,0.0002255,0.0004982552,0.007880769,0.152072,0.8280586,0.00006277024],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"commentary","genre_gemma":"commentary","genre_scores_codex":[0.009147748,0.1681901,0.001348783,0.771848,0.03392259,0.00002818386,0.000110305,0.0001301393,0.01527418],"genre_scores_gemma":[0.1600107,0.1071469,0.0009317357,0.5982065,0.1088945,0.0001053801,0.000214501,0.00007138893,0.02441837],"genre_candidate":"commentary","genre_consensus":"commentary","teacher_disagreement_score":0.01535429,"threshold_uncertainty_score":0.01630366,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01357884850240085,"score_gpt":0.2521683521259455,"score_spread":0.2385895036235446,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}