{"id":"W2093264695","doi":"10.1074/jbc.m100998200","title":"The Pyrimidine Ring-opened Derivative of 1,N 6-Ethenoadenine Is Excised from DNA by theEscherichia coli Fpg and Nth Proteins","year":2001,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"DNA Repair Mechanisms","field":"Biochemistry, Genetics and Molecular Biology","cited_by":25,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"","keywords":"Chemistry; DNA glycosylase; Pyrimidine; DNA; Escherichia coli; Stereochemistry; Ring (chemistry); Glycosidic bond; Uracil; Derivative (finance); Biochemistry; DNA repair; Enzyme; Organic chemistry","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002138551,0.0004926064,0.0003113933,0.0002117848,0.0001845143,0.0002002423,0.0002869583,0.0004345325,0.0009236843],"category_scores_gemma":[0.0001581152,0.0002703348,0.000395183,0.0001873058,0.0002474303,0.0001974012,0.0002272953,0.000736325,0.0008948859],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004738471,"about_ca_system_score_gemma":0.0002444488,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008721635,"about_ca_topic_score_gemma":0.001389599,"domain_scores_codex":[0.9997955,0.00003090267,0.00001641421,0.00006081079,0.00005722766,0.00003910732],"domain_scores_gemma":[0.9998258,0.00003237629,0.00005240627,0.0000340329,0.00001570437,0.0000396328],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00004281462,0.00001145699,0.00006724184,0.00002058361,0.000002307006,0.00003631599,0.000009120341,0.00003231777,0.9989725,0.00005027735,0.00001736785,0.0007376181],"study_design_scores_gemma":[0.000005355823,0.0000944585,0.001352049,0.000004965899,0.000004552886,0.0001749216,0.00001006787,0.0002103179,0.9956505,0.00002487161,0.002462998,0.000005039778],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9835454,0.001843921,0.01160911,0.0001105811,0.00006484936,0.00007546067,0.0006425839,0.0002092842,0.001898865],"genre_scores_gemma":[0.9603552,0.001191414,0.02181617,0.0001198834,0.00001706953,0.00005842756,0.004018303,0.0001141074,0.01230944],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0009236843,"threshold_uncertainty_score":0.003437996,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01418918416929097,"score_gpt":0.2377765366292937,"score_spread":0.2235873524600027,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}