{"id":"W2093273093","doi":"10.1016/j.mcn.2014.12.008","title":"Early growth response 2 (Egr-2) expression is triggered by NF-κB activation","year":2014,"lang":"en","type":"article","venue":"Molecular and Cellular Neuroscience","topic":"NF-κB Signaling Pathways","field":"Biochemistry, Genetics and Molecular Biology","cited_by":18,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Alberta; St. Boniface Hospital; University of Manitoba","funders":"Alzheimer's Society; University of Manitoba; Manitoba Health Research Council","keywords":"Chromatin immunoprecipitation; Biology; Gene knockdown; P50; Transcription factor; Molecular biology; NF-κB; Small interfering RNA; NFKB1; Cell biology; Protein subunit; Gene expression; Promoter; Transfection; Signal transduction; Gene; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001924032,0.0009083429,0.0003157772,0.0004465283,0.0002872651,0.0005537149,0.0002454872,0.0004312766,0.002207684],"category_scores_gemma":[0.000157332,0.0002466678,0.0005713892,0.0003395705,0.0003092156,0.0005043742,0.0004123771,0.001012558,0.0008471661],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006737489,"about_ca_system_score_gemma":0.0003392557,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007605575,"about_ca_topic_score_gemma":0.001088063,"domain_scores_codex":[0.9997448,0.00002347658,0.00001379656,0.00005571756,0.00005584438,0.0001062805],"domain_scores_gemma":[0.9998881,0.000009818165,0.00003610244,0.00001314743,0.00001706253,0.00003577826],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003384249,0.00002711026,0.0001379685,0.00004802232,0.000005921813,0.0001094038,0.0000169719,0.00002976555,0.9984022,0.0001993821,0.00008710675,0.0005976936],"study_design_scores_gemma":[0.00003288745,0.0001383429,0.008300955,0.00001770945,0.00001642912,0.0003778361,0.00009575883,0.0002932023,0.9872924,0.0002781565,0.003148039,0.00000820197],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9778838,0.006299654,0.007740737,0.0004506985,0.0002370448,0.00005371007,0.001537075,0.0003183827,0.005478879],"genre_scores_gemma":[0.9787337,0.003407782,0.004896259,0.0002931901,0.00005806196,0.000102718,0.002315854,0.00006003843,0.01013232],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002207684,"threshold_uncertainty_score":0.007385492,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006680673648619522,"score_gpt":0.2060643320735171,"score_spread":0.1993836584248976,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}